STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46930.1COG:COG1071: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit [Energy production and conversion]; Pfam:PF00676:Dehydrogenase, E1 component; Pfam:PF00676:Dehydrogenase, E1 component; SUPERFAMILY:SSF52518:No Description. (337 aa)    
Predicted Functional Partners:
AHY46931.1
COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 0.998
AHY45765.1
Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.992
AHY45863.1
COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 0.992
AHY47747.1
COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 0.992
AHY45713.1
COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 0.991
AHY46932.1
COG:COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes [Energy production and conversion]; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SUPERFAMILY:SSF52777:No Description.
 0.937
AHY46928.1
COG:COG4091: Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Pfam:PF03447:Aspartate/homoserine dehydrogenase, NAD-binding; Pfam:PF03447:Aspartate/homoserine dehydrogenase, NAD-binding; SUPERFAMILY:SSF51735:No Description.
 
     0.811
AHY45766.1
COG:COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes [Energy production and conversion]; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; ProSitePatterns:PS00189:2-oxo acid dehydrogenase, lipoyl-binding site; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SUPERFAMILY:SSF52777:No Description.
 0.797
AHY46927.1
COG:COG3731: Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Pfam:PF03829:Phosphotransferase system, glucitol/sorbitol-specific IIA component; Pfam:PF03829:Phosphotransferase system, glucitol/sorbitol-specific IIA component; ProSiteProfiles:PS51097:Phosphotransferase system, glucitol/sorbitol-specific IIA component; SUPERFAMILY:SSF141530:No Description.
  
    0.778
AHY46929.1
COG:COG2390: Transcriptional regulator contains sigma factor-related N-terminal domain [Transcription]; Pfam:PF04198:Sugar-binding domain, putative; Pfam:PF04198:Sugar-binding domain, putative; SUPERFAMILY:SSF100950:No Description.
       0.778
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.