STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46939.1COG:COG1349: Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Pfam:PF00455:DeoR C-terminal sensor domain; Pfam:PF00455:DeoR C-terminal sensor domain; PRINTS:PR00037:HTH DeoR N-terminal domain; ProSiteProfiles:PS51000:HTH DeoR N-terminal domain; SMART:SM00420:HTH DeoR N-terminal domain; SUPERFAMILY:SSF100950:No Description. (253 aa)    
Predicted Functional Partners:
AHY46938.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00584:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
 
  
 0.978
AHY46936.1
TIGRFAM:TIGR01427:Phosphotransferase system, fructose IIC component; COG:COG1299: Phosphotransferase system fructose-specific IIC component [Carbohydrate transport and metabolism]; Pfam:PF02302:Phosphotransferase system, EIIB component, type 2/3; ProSiteProfiles:PS51099:Phosphotransferase system, EIIB component, type 2; SUPERFAMILY:SSF52794:No Description; PTS_IIC_fructo.
 
  
 0.943
AHY45801.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00583:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
 
  
 0.888
AHY46937.1
TIGRFAM:TIGR00848:Phosphotransferase system, IIA component fructose subfamily; COG:COG1762: Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Pfam:PF00359:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; ProSiteProfiles:PS51094:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SUPERFAMILY:SSF55804:Phosphotransferase/anion transporter;KEGG: 00030; KEGG: 00540; KEGG: 00760.
 
  
 0.842
AHY46925.1
EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component; TIGRFAM:TIGR00821:Phosphotransferase system, enzyme II sorbitol-specific factor; COG:COG3730: Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Pfam:PF03608:Phosphotransferase system, enzyme II sorbitol-specific factor; PIRSF:PIRSF038321:Phosphotransferase system, enzyme II sorbitol-specific factor; ProSiteProfiles:PS51107:Phosphotransferase system, enzyme II sorbitol-specific factor.
 
 
    0.740
AHY45636.1
PRD domain; COG:COG3711: Transcriptional antiterminator [Transcription]; Pfam:PF00874:PRD; ProSiteProfiles:PS51372:PRD; SUPERFAMILY:SSF63520:PRD.
  
  
 0.738
AHY45689.1
ATP-grasp domain; COG:COG1042: Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Pfam:PF13549:ATP-grasp domain; ProSiteProfiles:PS51186:GNAT domain; SMART:SM00881:CoA-binding; SUPERFAMILY:SSF52210:Succinyl-CoA synthetase-like.
    
   0.726
AHY46926.1
COG:COG3732: Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Pfam:PF03612:Sorbitol phosphotransferase enzyme II, N-terminal; Pfam:PF03612:Sorbitol phosphotransferase enzyme II, N-terminal; ProSiteProfiles:PS51102:Sorbitol phosphotransferase enzyme II, N-terminal.
 
 
  
 0.599
AHY46934.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.533
AHY47000.1
COG:COG0394: Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Pfam:PF01451:Phosphotyrosine protein phosphatase I superfamily; Pfam:PF01451:Phosphotyrosine protein phosphatase I superfamily; SMART:SM00226:Phosphotyrosine protein phosphatase I superfamily; SUPERFAMILY:SSF52788:Phosphotyrosine protein phosphatase I superfamily; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.527
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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