STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46965.1TIGRFAM:TIGR01394:GTP-binding protein TypA; COG:COG1217: Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Pfam:PF00009:Elongation factor, GTP-binding domain; PRINTS:PR00315:Elongation factor, GTP-binding domain; ProSitePatterns:PS00301:Elongation factor, GTP-binding domain; SMART:SM00838:Translation elongation factor EFG, V domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; TypA_BipA. (593 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain; Catalyzes the synthesis of GMP from XMP.
  
  
 0.724
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.682
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.635
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
  
  
 0.633
trmD
trmD: tRNA (guanine(37)-N(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
  
 0.594
infC
infC: translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
 
 0.586
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.572
rpsI
COG:COG0103: Ribosomal protein S9 [Translation ribosomal structure and biogenesis]; Pfam:PF00380:Ribosomal protein S9; Hamap:MF_00532_B:Ribosomal protein S9, bacterial/plastid; Pfam:PF00380:Ribosomal protein S9; ProSitePatterns:PS00360:Ribosomal protein S9, conserved site; SUPERFAMILY:SSF54211:Ribosomal protein S5 domain 2-type fold; Belongs to the universal ribosomal protein uS9 family.
  
    0.555
rpoB
rpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.555
AHY47086.1
S1 RNA binding domain; COG:COG0539: Ribosomal protein S1 [Translation ribosomal structure and biogenesis]; Pfam:PF00575:Ribosomal protein S1, RNA-binding domain; PIRSF:PIRSF002111:Ribosomal protein S1; PRINTS:PR00681:Ribosomal protein S1; ProSiteProfiles:PS50126:Ribosomal protein S1, RNA-binding domain; SMART:SM00316:RNA-binding domain, S1; SUPERFAMILY:SSF50249:Nucleic acid-binding, OB-fold.
 
  
 0.554
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.