STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46975.1COG:COG1804: Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Pfam:PF02515:CoA-transferase family III; Pfam:PF02515:CoA-transferase family III; SUPERFAMILY:SSF89796:CoA-transferase family III domain; Belongs to the CoA-transferase III family. (389 aa)    
Predicted Functional Partners:
AHY46988.1
COG:COG2030: Acyl dehydratase [Lipid metabolism]; Pfam:PF01575:MaoC-like domain; Pfam:PF01575:MaoC-like domain; SUPERFAMILY:SSF54637:No Description.
  
 
 0.922
sucD
sucCoAalpha: succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.909
sucC
sucCoAbeta: succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.908
AHY47535.1
COG:COG2301: Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Pfam:PF03328:Aldehyde-lyase domain; Pfam:PF03328:Aldehyde-lyase domain; PIRSF:PIRSF015582:Citrate lyase, beta subunit; SUPERFAMILY:SSF51621:Pyruvate/Phosphoenolpyruvate kinase-like domain; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.865
AHY46976.1
COG:COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Pfam:PF12697:Alpha/beta hydrolase family; Pfam:PF12697:Alpha/beta hydrolase family; PRINTS:PR00412:Epoxide hydrolase-like; SUPERFAMILY:SSF53474:No Description.
  
    0.773
AHY46973.1
COG:COG1319: Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs [Energy production and conversion]; Pfam:PF00941:Molybdopterin dehydrogenase, FAD-binding; Pfam:PF00941:Molybdopterin dehydrogenase, FAD-binding; ProSiteProfiles:PS51387:FAD-binding, type 2; SMART:SM01092:CO dehydrogenase flavoprotein, C-terminal; SUPERFAMILY:SSF56176:FAD-binding, type 2.
       0.547
AHY46974.1
COG:COG2080: Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs [Energy production and conversion]; Pfam:PF01799:[2Fe-2S]-binding; Pfam:PF01799:[2Fe-2S]-binding; ProSitePatterns:PS00197:2Fe-2S ferredoxin, iron-sulphur binding site; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF47741:[2Fe-2S]-binding.
       0.546
AHY46972.1
COG:COG1529: Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs [Energy production and conversion]; Pfam:PF02738:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Pfam:PF02738:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; SMART:SM01008:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; SUPERFAMILY:SSF56003:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding.
       0.543
AHY46977.1
Fusaric acid resistance protein-like; COG:COG4129: Predicted membrane protein [Function unknown]; Pfam:PF13515:Fusaric acid resistance protein-like.
       0.466
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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