STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47000.1COG:COG0394: Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Pfam:PF01451:Phosphotyrosine protein phosphatase I superfamily; Pfam:PF01451:Phosphotyrosine protein phosphatase I superfamily; SMART:SM00226:Phosphotyrosine protein phosphatase I superfamily; SUPERFAMILY:SSF52788:Phosphotyrosine protein phosphatase I superfamily; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (155 aa)    
Predicted Functional Partners:
AHY45801.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00583:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
  
  
 0.724
AHY46938.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00584:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
  
  
 0.724
pgk
COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.698
AHY45447.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
  
 0.680
AHY46083.1
TIGRFAM:TIGR01064:Pyruvate kinase; COG:COG0469: Pyruvate kinase [Carbohydrate transport and metabolism]; Pfam:PF00224:Pyruvate kinase, barrel; PRINTS:PR01050:Pyruvate kinase; ProSitePatterns:PS00110:Pyruvate kinase, active site; SUPERFAMILY:SSF51621:Pyruvate/Phosphoenolpyruvate kinase-like domain;KEGG: 00010; KEGG: 00230; KEGG: 00620; KEGG: 00710; MetaCyc: PWY-2221; Reactome: REACT_474; UniPathway: UPA00109; pyruv_kin.
  
  
 0.670
AHY46622.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
  
 0.670
AHY45802.1
TIGRFAM:TIGR01068:Thioredoxin; COG:COG3118: Thioredoxin domain-containing protein [Posttranslational modification protein turnover chaperones]; Pfam:PF00085:Thioredoxin domain; PIRSF:PIRSF000077:Thioredoxin; PRINTS:PR00421:Thioredoxin; ProSiteProfiles:PS51352:Thioredoxin-like fold; SUPERFAMILY:SSF52833:Thioredoxin-like fold; Belongs to the thioredoxin family.
  
 
 0.657
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain; Catalyzes the synthesis of GMP from XMP.
     
 0.645
AHY47066.1
TIGRFAM:TIGR01534:Glyceraldehyde-3-phosphate dehydrogenase, type I; COG:COG0057: Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Pfam:PF02800:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PIRSF:PIRSF000149:Glyceraldehyde/Erythrose phosphate dehydrogenase family; PRINTS:PR00078:Glyceraldehyde/Erythrose phosphate dehydrogenase family; ProSitePatterns:PS00071:Glyceraldehyde 3-phosphate dehydrogenase, active site; SMART:SM00846:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SUPERFAMILY:SSF [...]
  
  
 0.631
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.628
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.