STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47025.1COG:COG2071: Predicted glutamine amidotransferases [General function prediction only]; Pfam:PF07722:Peptidase C26; Pfam:PF07722:Peptidase C26; ProSiteProfiles:PS51273:Glutamine amidotransferase; SUPERFAMILY:SSF52317:No Description. (268 aa)    
Predicted Functional Partners:
AHY47429.1
COG:COG2355: Zn-dependent dipeptidase microsomal dipeptidase homolog [Amino acid transport and metabolism]; Pfam:PF01244:Peptidase M19, renal dipeptidase; Pfam:PF01244:Peptidase M19, renal dipeptidase; ProSiteProfiles:PS51365:Peptidase M19, renal dipeptidase; SUPERFAMILY:SSF51556:No Description.
      0.904
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.714
AHY48034.1
COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; Pfam:PF00120:Glutamine synthetase, catalytic domain; SUPERFAMILY:SSF55931:No Description.
 
  
 0.542
AHY47023.1
COG:COG0470: ATPase involved in DNA replication [DNA replication recombination and repair]; Pfam:PF13177:DNA polymerase III, delta subunit; Pfam:PF13177:DNA polymerase III, delta subunit; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
   
   0.525
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.476
AHY45624.1
MerR HTH family regulatory protein; COG:COG0789: Predicted transcriptional regulators [Transcription]; Pfam:PF13411:MerR HTH family regulatory protein; ProSitePatterns:PS00552:Transcription regulator HTH, MerR; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00422:Transcription regulator HTH, MerR; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
 
  
 0.423
AHY47735.1
Helix-turn-helix domain; COG:COG0662: Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Pfam:PF13560:Helix-turn-helix domain; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00530:Helix-turn-helix; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
 
  
 0.420
AHY46403.1
TIGRFAM:TIGR00653:Glutamine synthetase type I; COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; ProSitePatterns:PS00181:Glutamine synthetase, glycine-rich site; SUPERFAMILY:SSF55931:No Description;KEGG: 00250; KEGG: 00330; KEGG: 00910; MetaCyc: PWY-3282.
  
  
 0.414
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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