STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47032.1Tetratricopeptide repeat; COG:COG4235: Cytochrome c biogenesis factor [Posttranslational modification protein turnover chaperones]; Pfam:PF13428:Tetratricopeptide repeat; ProSiteProfiles:PS50005:Tetratricopeptide repeat; SUPERFAMILY:SSF48452:No Description. (214 aa)    
Predicted Functional Partners:
alaS
alaS: alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.727
AHY47183.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COG:COG4251: Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50109:Signal transduction histidine kinase, core; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain.
   
 
 0.697
AHY46004.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2200: FOG: EAL domain [Signal transduction mechanisms]; Pfam:PF00563:Diguanylate phosphodiesterase, EAL domain; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00052:Diguanylate phosphodiesterase, EAL domain; SUPERFAMILY:SSF141868:Diguanylate phosphodiesterase, EAL domain; sensory_box.
   
 
 0.694
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.676
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.667
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.667
rpoB
rpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.663
AHY47033.1
COG:COG0142: Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Pfam:PF00348:Polyprenyl synthetase; Pfam:PF00348:Polyprenyl synthetase; ProSitePatterns:PS00444:Polyprenyl synthetase; SUPERFAMILY:SSF48576:Terpenoid synthase; Belongs to the FPP/GGPP synthase family.
   
   0.661
AHY47824.1
GGDEF: diguanylate cyclase (GGDEF) domain; TIGRFAM:TIGR00254:GGDEF domain; COG:COG5001: Predicted signal transduction protein containing a membrane domain an EAL and a GGDEF domain [Signal transduction mechanisms]; Pfam:PF00563:Diguanylate phosphodiesterase, EAL domain; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00052:Diguanylate phosphodiesterase, EAL domain; SUPERFAMILY:SSF141868:Diguanylate phosphodiesterase, EAL domain.
   
 
 0.653
AHY46622.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.648
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.