STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmBPutative S-adenosylmethionine-dependent methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (225 aa)    
Predicted Functional Partners:
truB
TruB: tRNA pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
 
 0.750
AHY47087.1
COG:COG0749: DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication recombination and repair]; Pfam:PF00476:DNA-directed DNA polymerase, family A, palm domain; PRINTS:PR00868:DNA polymerase A; ProSitePatterns:PS00447:DNA-directed DNA polymerase, family A, conserved site; SMART:SM00475:5'-3' exonuclease, N-terminal; SUPERFAMILY:SSF56672:No Description.
  
  
 0.637
AHY47089.1
Helix-turn-helix domain; COG:COG4189: Predicted transcriptional regulator [Transcription]; Pfam:PF12840:Helix-turn-helix domain; ProSiteProfiles:PS50987:HTH ArsR-type DNA-binding domain; SMART:SM00418:HTH ArsR-type DNA-binding domain; SUPERFAMILY:SSF46785:No Description.
 
     0.605
truA
tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.591
rpmD
TIGRFAM:TIGR01308:Ribosomal protein L30, bacterial-type; COG:COG1841: Ribosomal protein L30/L7E [Translation ribosomal structure and biogenesis]; Pfam:PF00327:Ribosomal protein L30, ferredoxin-like fold domain; Hamap:MF_01371_B:Ribosomal protein L30, bacterial-type; PIRSF:PIRSF002211:Ribosomal protein L30, bacterial-type; SUPERFAMILY:SSF55129:Ribosomal protein L30, ferredoxin-like fold domain; rpmD_bact.
   
    0.561
serS
serS: serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
 
 0.543
AHY47088.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.540
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
   
  
 0.534
AHY46460.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF53335:No Description.
  
  
 0.526
AHY47086.1
S1 RNA binding domain; COG:COG0539: Ribosomal protein S1 [Translation ribosomal structure and biogenesis]; Pfam:PF00575:Ribosomal protein S1, RNA-binding domain; PIRSF:PIRSF002111:Ribosomal protein S1; PRINTS:PR00681:Ribosomal protein S1; ProSiteProfiles:PS50126:Ribosomal protein S1, RNA-binding domain; SMART:SM00316:RNA-binding domain, S1; SUPERFAMILY:SSF50249:Nucleic acid-binding, OB-fold.
  
    0.513
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.