STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47160.1COG:COG0025: NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Pfam:PF00999:Cation/H+ exchanger; Pfam:PF00999:Cation/H+ exchanger. (431 aa)    
Predicted Functional Partners:
AHY46208.1
Pfam:PF11338:Protein of unknown function DUF3140.
 
     0.820
AHY46606.1
Hypothetical protein; COG:COG4850: Uncharacterized conserved protein [Function unknown]; Pfam:PF09949:Domain of unknown function DUF2183; Pfam:PF09949:Domain of unknown function DUF2183.
  
     0.629
AHY47654.1
COG:COG2124: Cytochrome P450 [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00067:Cytochrome P450; SUPERFAMILY:SSF48264:Cytochrome P450;Reactome: REACT_13433.
  
 
   0.515
AHY47161.1
COG:COG0134: Indole-3-glycerol phosphate synthase [Amino acid transport and metabolism]; Pfam:PF00218:Indole-3-glycerol phosphate synthase; Pfam:PF00218:Indole-3-glycerol phosphate synthase; ProSitePatterns:PS00614:Indole-3-glycerol phosphate synthase, conserved site; SUPERFAMILY:SSF51366:Ribulose-phosphate binding barrel; Belongs to the TrpC family.
  
    0.500
trpD
trpD: anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
       0.500
AHY47163.1
Glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; TIGRFAM:TIGR00566:Anthranilate synthase/para-aminobenzoate synthase like domain; COG:COG0512: Anthranilate/para-aminobenzoate synthases component II [Amino acid transport and metabolism / Coenzyme metabolism]; Pfam:PF00117:Glutamine amidotransferase; PRINTS:PR00097:Anthranilate synthase component II signature; ProSiteProfiles:PS51273:Glutamine amidotransferase; SUPERFAMILY:SSF52317:No Description;KEGG: 00400; MetaCyc: PWY-5958; UniPathway: UPA00035; trpG_papA.
       0.500
AHY46494.1
TIGRFAM:TIGR02271:Domain of unknown function DUF2382; COG:COG3861: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF09557:Domain of unknown function DUF2382; SUPERFAMILY:SSF50346:PRC-barrel-like.
  
     0.467
AHY47314.1
COG:COG0475: Kef-type K+ transport systems membrane components [Inorganic ion transport and metabolism]; Pfam:PF00999:Cation/H+ exchanger; Pfam:PF00999:Cation/H+ exchanger.
   
 
 0.457
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 
 
 0.433
AHY45745.1
COG:COG1514: 2'-5' RNA ligase [Translation ribosomal structure and biogenesis]; Pfam:PF13563:2'-5' RNA ligase superfamily; SUPERFAMILY:SSF55144:RNA ligase/cyclic nucleotide phosphodiesterase.
 
     0.415
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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