STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47241.1COG:COG3688: Predicted RNA-binding protein containing a PIN domain [General function prediction only]; Pfam:PF05991:Protein of unknown function DUF901; Pfam:PF05991:Protein of unknown function DUF901. (167 aa)    
Predicted Functional Partners:
cysS
cysS: cysteine--tRNA ligase; TIGRFAM:TIGR00435:Cysteine-tRNA ligase; COG:COG0215: Cysteinyl-tRNA synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF01406:Cysteinyl-tRNA synthetase/mycothiol ligase; Hamap:MF_00041:Cysteine-tRNA ligase; PRINTS:PR00983:Cysteinyl-tRNA synthetase/mycothiol ligase; SMART:SM00840:Cysteinyl-tRNA synthetase, class Ia, DALR; SUPERFAMILY:SSF52374:No Description;KEGG: 00970; Reactome: REACT_71; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.930
AHY47242.1
RNA methyltransferase, TrmH family, group 3; TIGRFAM:TIGR00186:RNA methyltransferase TrmH family; COG:COG0566: rRNA methylases [Translation ribosomal structure and biogenesis]; Pfam:PF00588:tRNA/rRNA methyltransferase, SpoU; SMART:SM00967:RNA 2-O ribose methyltransferase, substrate binding; SUPERFAMILY:SSF75217:No Description;KEGG: 00130; KEGG: 00253; KEGG: 00340; KEGG: 00350; KEGG: 00360; KEGG: 00380; KEGG: 00402; KEGG: 00522; KEGG: 00624; KEGG: 00680; KEGG: 00860; KEGG: 00906; KEGG: 00940; KEGG: 00941; KEGG: 00942; KEGG: 00945; KEGG: 00950; KEGG: 00981; rRNA_methyl_3; Belongs to the [...]
  
  
 0.905
AHY47247.1
COG:COG1623: Predicted nucleic-acid-binding protein (contains the HHH domain) [General function prediction only]; Pfam:PF10635:DNA integrity scanning, DisA, linker region; Pfam:PF10635:DNA integrity scanning, DisA, linker region; SUPERFAMILY:SSF143597:No Description; Belongs to the DisA family.
 
     0.839
ispF
ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.795
ispD
ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
       0.791
radA
Sms: DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.791
gltX
Glutamyl- and glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.788
AHY46563.1
COG:COG0566: rRNA methylases [Translation ribosomal structure and biogenesis]; Pfam:PF00588:tRNA/rRNA methyltransferase, SpoU; SUPERFAMILY:SSF75217:No Description.
  
  
 0.525
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
    0.401
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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