Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHY47285.1COG:COG2804: Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00437:Type II secretion system protein E; Pfam:PF00437:Type II secretion system protein E; ProSitePatterns:PS00662:Type II secretion system protein E; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase. (560 aa)    
Predicted Functional Partners:
AHY46146.1
COG:COG1459: Type II secretory pathway component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00482:Type II secretion system F domain; Pfam:PF00482:Type II secretion system F domain; PRINTS:PR00812:GspF/PilC family; ProSitePatterns:PS00874:Type II secretion system conserved site.
 
 0.944
AHY46649.1
COG:COG1459: Type II secretory pathway component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00482:Type II secretion system F domain; Pfam:PF00482:Type II secretion system F domain; PRINTS:PR00812:GspF/PilC family; ProSitePatterns:PS00874:Type II secretion system conserved site.
 
 0.942
AHY46135.1
COG:COG1989: Type II secretory pathway prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification protein turnover chaperones / Intracellular trafficking and secretion]; Pfam:PF06750:Peptidase A24A, N-terminal; Pfam:PF06750:Peptidase A24A, N-terminal.
 
 
 0.862
AHY46755.1
TIGRFAM:TIGR01175:Type IV pilus assembly protein PilM; COG:COG4972: Tfp pilus assembly protein ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF11104:Type IV pilus assembly protein PilM; SUPERFAMILY:SSF53067:No Description.
 
 
 0.814
AHY46138.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG2165: Type II secretory pathway pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF13544:Prokaryotic N-terminal methylation site; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
 
 
 0.775
AHY47286.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG4969: Tfp pilus assembly protein major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF13544:Prokaryotic N-terminal methylation site; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
 
   
 0.684
AHY46809.1
TIGRFAM:TIGR00360:ComEC/Rec2-related protein; COG:COG0658: Predicted membrane metal-binding protein [General function prediction only]; Pfam:PF03772:ComEC/Rec2-related protein; ComEC_N-term.
  
  
 0.633
AHY46140.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG4795: Type II secretory pathway component PulJ [Intracellular trafficking and secretion]; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
  
 
 0.624
AHY46142.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG4970: Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF07963:Prokaryotic N-terminal methylation site; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
  
 
 0.624
AHY45338.1
TIGRFAM:TIGR00621:Single-strand DNA-binding; COG:COG0629: Single-stranded DNA-binding protein [DNA replication recombination and repair]; Pfam:PF00436:Primosome PriB/single-strand DNA-binding; PIRSF:PIRSF002070:Single-strand DNA-binding; ProSiteProfiles:PS50935:Primosome PriB/single-strand DNA-binding; SUPERFAMILY:SSF50249:Nucleic acid-binding, OB-fold.
  
  
 0.561
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.