STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47314.1COG:COG0475: Kef-type K+ transport systems membrane components [Inorganic ion transport and metabolism]; Pfam:PF00999:Cation/H+ exchanger; Pfam:PF00999:Cation/H+ exchanger. (435 aa)    
Predicted Functional Partners:
AHY46833.1
Sodium/hydrogen exchanger family; COG:COG4651: Kef-type K+ transport system predicted NAD-binding component [Inorganic ion transport and metabolism]; Pfam:PF00999:Cation/H+ exchanger; ProSiteProfiles:PS51202:Regulator of K+ conductance, C-terminal; SUPERFAMILY:SSF51735:No Description; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.789
AHY46916.1
HAD ATPase, P-type, family IC; TIGRFAM:TIGR01494:Cation-transporting P-type ATPase; COG:COG0474: Cation transport ATPase [Inorganic ion transport and metabolism]; Pfam:PF00122:P-type ATPase, A domain; PRINTS:PR00119:Cation-transporting P-type ATPase; ProSitePatterns:PS00154:P-type ATPase, phosphorylation site; SMART:SM00831:Cation-transporting P-type ATPase, N-terminal; SUPERFAMILY:SSF81665:No Description; ATPase_P-type.
  
 
 0.644
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.639
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.631
AHY45891.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50112:PAS domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
 
   
 0.629
AHY47313.1
COG:COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes [Energy production and conversion]; Pfam:PF02852:Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Pfam:PF02852:Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRINTS:PR00411:Pyridine nucleotide disulphide reductase class-I signature; ProSitePatterns:PS00837:Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2; SUPERFAMILY:SSF51905:No Description.
  
  
 0.605
AHY46980.1
Heavy metal translocating P-type ATPase; TIGRFAM:TIGR01525:Cation-transporting P-type ATPase, subfamily IB; COG:COG2217: Cation transport ATPase [Inorganic ion transport and metabolism]; Pfam:PF00122:P-type ATPase, A domain; PRINTS:PR00119:Cation-transporting P-type ATPase; ProSitePatterns:PS01047:Heavy-metal-associated, conserved site; ProSiteProfiles:PS50846:Heavy metal-associated domain, HMA; SUPERFAMILY:SSF56784:HAD-like domain; ATPase-IB_hvy.
  
  
 0.598
AHY45979.1
TIGRFAM:TIGR01304:IMP dehydrogenase-related 2; COG:COG0516: IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]; Pfam:PF00478:IMP dehydrogenase/GMP reductase; SUPERFAMILY:SSF51412:No Description;KEGG: 00121; KEGG: 00231; KEGG: 00520; KEGG: 00592; KEGG: 00633; KEGG: 00860; KEGG: 00906; KEGG: 00950; KEGG: 00981; IMP_DH_rel_2.
  
  
 0.558
AHY47707.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50885:HAMP linker domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
 
   
 0.531
AHY47312.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.497
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.