STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47331.1Polysulfide reductase, NrfD; COG:COG0437: Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Pfam:PF03916:NrfD family; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF54862:No Description. (555 aa)    
Predicted Functional Partners:
AHY47330.1
Molybdopterin oxidoreductase; COG:COG0243: Anaerobic dehydrogenases typically selenocysteine-containing [Energy production and conversion]; Pfam:PF00384:Molybdopterin oxidoreductase; SMART:SM00926:Molybdopterin oxidoreductase, 4Fe-4S domain; SUPERFAMILY:SSF53706:No Description; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.991
AHY47854.1
Molybdopterin oxidoreductase; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF00384:Molybdopterin oxidoreductase; SUPERFAMILY:SSF53706:No Description; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.916
AHY47855.1
Molybdopterin oxidoreductase Fe4S4 domain; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF04879:Molybdopterin oxidoreductase, 4Fe-4S domain; SMART:SM00926:Molybdopterin oxidoreductase, 4Fe-4S domain; SUPERFAMILY:SSF53706:No Description.
 
  
 0.768
AHY47864.1
Molybdopterin oxidoreductase; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF00384:Molybdopterin oxidoreductase; SUPERFAMILY:SSF53706:No Description; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.649
AHY47863.1
Molybdopterin oxidoreductase Fe4S4 domain; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF04879:Molybdopterin oxidoreductase, 4Fe-4S domain; ProSitePatterns:PS00551:Molybdopterin oxidoreductase, molybdopterin cofactor binding site; SMART:SM00926:Molybdopterin oxidoreductase, 4Fe-4S domain; SUPERFAMILY:SSF53706:No Description.
 
  
 0.634
tuf
EF-Tu: translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.623
AHY47240.1
TIGRFAM:TIGR00485:Translation elongation factor EFTu/EF1A, bacterial/organelle; COG:COG0050: GTPases - translation elongation factors [Translation ribosomal structure and biogenesis]; Pfam:PF00009:Elongation factor, GTP-binding domain; Hamap:MF_00118_B:Translation elongation factor EFTu/EF1A, bacterial/organelle; PRINTS:PR00315:Elongation factor, GTP-binding domain; ProSitePatterns:PS00301:Elongation factor, GTP-binding domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.623
AHY46507.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
   
    0.586
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.586
AHY47649.1
COG:COG0243: Anaerobic dehydrogenases typically selenocysteine-containing [Energy production and conversion]; Pfam:PF00384:Molybdopterin oxidoreductase; Pfam:PF00384:Molybdopterin oxidoreductase; ProSitePatterns:PS00490:Molybdopterin oxidoreductase, prokaryotic, conserved site; SMART:SM00926:Molybdopterin oxidoreductase, 4Fe-4S domain; SUPERFAMILY:SSF53706:No Description; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.572
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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