STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pdxHpdxH: pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa)    
Predicted Functional Partners:
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.945
pdxS
TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
    
 0.935
pdxY
Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
 
  
 0.932
AHY47350.1
COG:COG2343: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF04248:Protein of unknown function DUF427; Pfam:PF04248:Protein of unknown function DUF427.
       0.773
carB
TIGRFAM:TIGR01369:Carbamoyl-phosphate synthase, large subunit; COG:COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Hamap:MF_01210_B:Carbamoyl-phosphate synthase, large subunit; PRINTS:PR00098:Carbamoyl-phosphate synthase large subunit, CPSase domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50975:ATP-grasp fold; SMART:SM01096:Carbamoyl [...]
 
 
  
 0.751
AHY47352.1
COG:COG2816: NTP pyrophosphohydrolases containing a Zn-finger probably nucleic-acid-binding [DNA replication recombination and repair]; Pfam:PF00293:NUDIX hydrolase domain; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
  
    0.728
AHY47351.1
COG:COG0251: Putative translation initiation inhibitor yjgF family [Translation ribosomal structure and biogenesis]; Pfam:PF01042:YjgF/Yer057p/UK114 family; Pfam:PF01042:YjgF/Yer057p/UK114 family; SUPERFAMILY:SSF55298:Endoribonuclease L-PSP/chorismate mutase-like.
  
    0.725
AHY47353.1
FAD linked oxidase, C-terminal domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF02913:FAD-linked oxidase, C-terminal; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF55103:FAD-linked oxidase-like, C-terminal.
       0.718
carA
TIGRFAM:TIGR01368:Carbamoyl-phosphate synthase, small subunit; COG:COG0505: Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF00988:Carbamoyl-phosphate synthase, small subunit N-terminal domain; Hamap:MF_01209:Carbamoyl-phosphate synthase, small subunit; PRINTS:PR00099:Carbamoyl-phosphate synthase protein GATase domain signature; ProSiteProfiles:PS51273:Glutamine amidotransferase; SMART:SM01097:Carbamoyl-phosphate synthase, small subunit N-terminal domain; SUPERFAMILY:SSF52317:No Description;KEGG: 00240; KEGG: [...]
 
      0.582
ribBA
ribA: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.540
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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