STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AHY47351.1COG:COG0251: Putative translation initiation inhibitor yjgF family [Translation ribosomal structure and biogenesis]; Pfam:PF01042:YjgF/Yer057p/UK114 family; Pfam:PF01042:YjgF/Yer057p/UK114 family; SUPERFAMILY:SSF55298:Endoribonuclease L-PSP/chorismate mutase-like. (135 aa)    
Predicted Functional Partners:
AHY47352.1
COG:COG2816: NTP pyrophosphohydrolases containing a Zn-finger probably nucleic-acid-binding [DNA replication recombination and repair]; Pfam:PF00293:NUDIX hydrolase domain; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
  
    0.776
AHY47353.1
FAD linked oxidase, C-terminal domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF02913:FAD-linked oxidase, C-terminal; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF55103:FAD-linked oxidase-like, C-terminal.
       0.773
pdxH
pdxH: pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  
    0.725
AHY47350.1
COG:COG2343: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF04248:Protein of unknown function DUF427; Pfam:PF04248:Protein of unknown function DUF427.
       0.718
AHY47354.1
TIGRFAM:TIGR01536:Asparagine synthase, glutamine-hydrolyzing; COG:COG0367: Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Pfam:PF00733:Asparagine synthase; PIRSF:PIRSF001589:Asparagine synthase, glutamine-hydrolyzing; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF52402:No Description;KEGG: 00250; KEGG: 00910; UniPathway: UPA00134; asn_synth_AEB.
       0.465
AHY45685.1
COG:COG2070: Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Pfam:PF03060:2-nitropropane dioxygenase, NPD; Pfam:PF03060:2-nitropropane dioxygenase, NPD; ProSitePatterns:PS00912:Dihydroorotate dehydrogenase, conserved site; SUPERFAMILY:SSF51412:No Description.
 
      0.439
AHY47347.1
COG:COG1960: Acyl-CoA dehydrogenases [Lipid metabolism]; Pfam:PF02771:Acyl-CoA dehydrogenase, N-terminal; Pfam:PF02771:Acyl-CoA dehydrogenase, N-terminal; SUPERFAMILY:SSF56645:Acyl-CoA dehydrogenase/oxidase.
   
   0.433
AHY45782.1
COG:COG0480: Translation elongation factors (GTPases) [Translation ribosomal structure and biogenesis]; Pfam:PF03764:Translation elongation factor EFG/EF2, domain IV; Pfam:PF03764:Translation elongation factor EFG/EF2, domain IV; PRINTS:PR00315:Elongation factor, GTP-binding domain; SMART:SM00889:Translation elongation factor EFG/EF2, domain IV; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
   
  0.427
fusA
EF-G: translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/ [...]
   
  0.427
AHY47345.1
Pyridine nucleotide-disulfide oxidoreductase; COG:COG1251: NAD(P)H-nitrite reductase [Energy production and conversion]; Pfam:PF07992:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; PRINTS:PR00368:FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SUPERFAMILY:SSF51905:No Description.
       0.408
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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