STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47354.1TIGRFAM:TIGR01536:Asparagine synthase, glutamine-hydrolyzing; COG:COG0367: Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Pfam:PF00733:Asparagine synthase; PIRSF:PIRSF001589:Asparagine synthase, glutamine-hydrolyzing; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF52402:No Description;KEGG: 00250; KEGG: 00910; UniPathway: UPA00134; asn_synth_AEB. (519 aa)    
Predicted Functional Partners:
argG
TIGRFAM:TIGR00032:Argininosuccinate synthase; COG:COG0137: Argininosuccinate synthase [Amino acid transport and metabolism]; Pfam:PF00764:Argininosuccinate synthase; Hamap:MF_00005:Argininosuccinate synthase, type 1 subfamily; ProSitePatterns:PS00565:Argininosuccinate synthase, conserved site; SUPERFAMILY:SSF69864:No Description;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.917
AHY46968.1
COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; Pfam:PF00155:Aminotransferase, class I/classII; ProSitePatterns:PS00105:Aminotransferases, class-I, pyridoxal-phosphate-binding site; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
  
 
 0.916
purA
purA: adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.915
pyrB
TIGRFAM:TIGR00670:Aspartate carbamoyltransferase; COG:COG0540: Aspartate carbamoyltransferase catalytic chain [Nucleotide transport and metabolism]; Pfam:PF02729:Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Hamap:MF_00001:Aspartate carbamoyltransferase; PRINTS:PR00101:Aspartate carbamoyltransferase; ProSitePatterns:PS00097:Aspartate/ornithine carbamoyltransferase; SUPERFAMILY:SSF53671:Aspartate/ornithine carbamoyltransferase;KEGG: 00240; KEGG: 00250; MetaCyc: PWY-5686; UniPathway: UPA00070; asp_carb_tr; Belongs to the aspartate/ornithine carbamoyltransferase superfami [...]
  
 
 0.914
AHY47134.1
COG:COG0252: L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D [Amino acid transport and metabolism / Translation ribosomal structure and biogenesis]; Pfam:PF00710:Asparaginase/glutaminase; Pfam:PF00710:Asparaginase/glutaminase; PIRSF:PIRSF001220:Asparaginase/glutaminase; PRINTS:PR00139:Asparaginase/glutaminase; SMART:SM00870:Asparaginase/glutaminase; SUPERFAMILY:SSF53774:Asparaginase/glutaminase.
     
 0.910
AHY45373.1
COG:COG0029: Aspartate oxidase [Coenzyme metabolism]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; PRINTS:PR00368:FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SUPERFAMILY:SSF51905:No Description.
     
  0.900
AHY46331.1
TIGRFAM:TIGR00657:Aspartate kinase domain; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kinases; Belongs to the aspartokinase family.
  
 
 0.849
AHY47938.1
TIGRFAM:TIGR00656:Aspartate kinase, monofunctional class; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; PIRSF:PIRSF000726:Aspartate kinase, monofunctional class; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kin_monofn; Belongs to the aspartokinase family.
  
 
 0.849
gatB
gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
 
 0.571
gatC
gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
    
 0.545
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.