STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47400.1COG:COG2872: Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Pfam:PF01411:Alanyl-tRNA synthetase, class IIc, N-terminal; Pfam:PF01411:Alanyl-tRNA synthetase, class IIc, N-terminal; SUPERFAMILY:SSF50447:Translation elongation/initiation factor/Ribosomal, beta-barrel. (241 aa)    
Predicted Functional Partners:
alaS
alaS: alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
 0.916
AHY47399.1
COG:COG1430: Uncharacterized conserved protein [Function unknown]; Pfam:PF02643:Protein of unknown function DUF192.
       0.773
AHY47401.1
TIGRFAM:TIGR01856:Histidinol phosphate phosphatase, HisJ; COG:COG1387: Histidinol phosphatase and related hydrolases of the PHP family [Amino acid transport and metabolism / General function prediction only]; Pfam:PF02811:PHP, C-terminal; SUPERFAMILY:SSF89550:Polymerase/histidinol phosphatase-like;UniPathway: UPA00031; hisJ_fam; Belongs to the PHP hydrolase family. HisK subfamily.
       0.773
AHY47402.1
Glycosyl transferases group 1; COG:COG0438: Glycosyltransferase [Cell envelope biogenesis outer membrane]; Pfam:PF00534:Glycosyl transferase, family 1; SUPERFAMILY:SSF53756:No Description.
       0.625
AHY47403.1
COG:COG0720: 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Pfam:PF01242:6-pyruvoyl tetrahydropterin synthase/QueD family protein; Pfam:PF01242:6-pyruvoyl tetrahydropterin synthase/QueD family protein; PIRSF:PIRSF006113:6-pyruvoyl tetrahydropterin synthase/QueD family protein; SUPERFAMILY:SSF55620:No Description.
       0.625
AHY47404.1
COG:COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; SMART:SM00829:Polyketide synthase, enoylreductase; SUPERFAMILY:SSF51735:No Description.
       0.550
AHY47405.1
TIGRFAM:TIGR00227:Riboflavin-specific deaminase, C-terminal; COG:COG1985: Pyrimidine reductase riboflavin biosynthesis [Coenzyme metabolism]; Pfam:PF01872:Bacterial bifunctional deaminase-reductase, C-terminal; SUPERFAMILY:SSF53597:Dihydrofolate reductase-like domain;KEGG: 00740; UniPathway: UPA00275; ribD_Cterm.
       0.550
AHY47639.1
RecF/RecN/SMC N terminal domain; COG:COG0419: ATPase involved in DNA repair [DNA replication recombination and repair]; Pfam:PF02463:RecF/RecN/SMC; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
     0.487
ileS
ileS: isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
   
 0.434
AHY47406.1
folB: dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.419
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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