STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47405.1TIGRFAM:TIGR00227:Riboflavin-specific deaminase, C-terminal; COG:COG1985: Pyrimidine reductase riboflavin biosynthesis [Coenzyme metabolism]; Pfam:PF01872:Bacterial bifunctional deaminase-reductase, C-terminal; SUPERFAMILY:SSF53597:Dihydrofolate reductase-like domain;KEGG: 00740; UniPathway: UPA00275; ribD_Cterm. (246 aa)    
Predicted Functional Partners:
ribBA
ribA: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 0.999
AHY46654.1
ribE: riboflavin synthase, alpha subunit; TIGRFAM:TIGR00187:Lumazine-binding protein; COG:COG0307: Riboflavin synthase alpha chain [Coenzyme metabolism]; Pfam:PF00677:Lumazine-binding domain; PIRSF:PIRSF000498:Lumazine-binding protein; ProSiteProfiles:PS51177:Lumazine-binding domain; SUPERFAMILY:SSF63380:Riboflavin synthase-like beta-barrel;KEGG: 00740; MetaCyc: PWY-6167; UniPathway: UPA00275.
  
 0.929
AHY46653.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 
0.922
ribH
Lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.908
AHY47404.1
COG:COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; SMART:SM00829:Polyketide synthase, enoylreductase; SUPERFAMILY:SSF51735:No Description.
 
    0.833
AHY47403.1
COG:COG0720: 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Pfam:PF01242:6-pyruvoyl tetrahydropterin synthase/QueD family protein; Pfam:PF01242:6-pyruvoyl tetrahydropterin synthase/QueD family protein; PIRSF:PIRSF006113:6-pyruvoyl tetrahydropterin synthase/QueD family protein; SUPERFAMILY:SSF55620:No Description.
     
 0.705
AHY47402.1
Glycosyl transferases group 1; COG:COG0438: Glycosyltransferase [Cell envelope biogenesis outer membrane]; Pfam:PF00534:Glycosyl transferase, family 1; SUPERFAMILY:SSF53756:No Description.
     
 0.680
AHY47406.1
folB: dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.612
AHY47399.1
COG:COG1430: Uncharacterized conserved protein [Function unknown]; Pfam:PF02643:Protein of unknown function DUF192.
       0.550
AHY47400.1
COG:COG2872: Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Pfam:PF01411:Alanyl-tRNA synthetase, class IIc, N-terminal; Pfam:PF01411:Alanyl-tRNA synthetase, class IIc, N-terminal; SUPERFAMILY:SSF50447:Translation elongation/initiation factor/Ribosomal, beta-barrel.
       0.550
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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