STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47424.1TIGRFAM:TIGR01136:Cysteine synthase K/M; COG:COG0031: Cysteine synthase [Amino acid transport and metabolism]; Pfam:PF00291:Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily; ProSitePatterns:PS00901:Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site; SUPERFAMILY:SSF53686:Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily;KEGG: 00270; KEGG: 00450; KEGG: 00920; UniPathway: UPA00136. (306 aa)    
Predicted Functional Partners:
AHY47425.1
COG:COG1310: Predicted metal-dependent protease of the PAD1/JAB1 superfamily [General function prediction only]; Pfam:PF14464:Prokaryotic homologs of the JAB domain; Pfam:PF14464:Prokaryotic homologs of the JAB domain; SMART:SM00232:JAB1/Mov34/MPN/PAD-1; SUPERFAMILY:SSF102712:No Description.
   0.955
AHY47426.1
COG:COG1977: Molybdopterin converting factor small subunit [Coenzyme metabolism]; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; SUPERFAMILY:SSF54285:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp.
 
 
 0.955
cysS
cysS: cysteine--tRNA ligase; TIGRFAM:TIGR00435:Cysteine-tRNA ligase; COG:COG0215: Cysteinyl-tRNA synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF01406:Cysteinyl-tRNA synthetase/mycothiol ligase; Hamap:MF_00041:Cysteine-tRNA ligase; PRINTS:PR00983:Cysteinyl-tRNA synthetase/mycothiol ligase; SMART:SM00840:Cysteinyl-tRNA synthetase, class Ia, DALR; SUPERFAMILY:SSF52374:No Description;KEGG: 00970; Reactome: REACT_71; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.931
AHY45698.1
COG:COG0626: Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Pfam:PF01053:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; Pfam:PF01053:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PIRSF:PIRSF001434:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; ProSitePatterns:PS00868:Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
 
 0.833
AHY47427.1
ThiF family; COG:COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Pfam:PF00899:UBA/THIF-type NAD/FAD binding fold; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF69572:Molybdenum cofactor biosynthesis, MoeB.
 
 
 0.730
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
     
 0.637
cysC
apsK: adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.625
AHY46157.1
COG:COG0155: Sulfite reductase beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Pfam:PF01077:Nitrite/sulphite reductase 4Fe-4S domain; Pfam:PF01077:Nitrite/sulphite reductase 4Fe-4S domain; PRINTS:PR00397:Nitrite/sulphite reductase iron-sulphur/siroheam-binding site; ProSitePatterns:PS00365:Nitrite/sulphite reductase iron-sulphur/siroheam-binding site; SUPERFAMILY:SSF56014:No Description.
  
  
 0.599
AHY46156.1
cysH: phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
  
 0.597
AHY45673.1
TIGRFAM:TIGR01682:Molybdopterin converting factor, subunit 1; COG:COG1977: Molybdopterin converting factor small subunit [Coenzyme metabolism]; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; SUPERFAMILY:SSF54285:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp;UniPathway: UPA00344.
  
 
 0.490
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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