node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHY45548.1 | AHY47471.1 | RradSPS_0265 | RradSPS_2188 | T6PP: trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.587 |
AHY45548.1 | pgk | RradSPS_0265 | RradSPS_1782 | T6PP: trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.505 |
AHY46012.1 | AHY46013.1 | RradSPS_0729 | RradSPS_0730 | metH: methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase. | 0.999 |
AHY46012.1 | AHY47471.1 | RradSPS_0729 | RradSPS_2188 | metH: methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.539 |
AHY46013.1 | AHY46012.1 | RradSPS_0730 | RradSPS_0729 | Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase. | metH: methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
AHY46013.1 | AHY47471.1 | RradSPS_0730 | RradSPS_2188 | Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.598 |
AHY46013.1 | pgk | RradSPS_0730 | RradSPS_1782 | Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase. | COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.625 |
AHY47113.1 | AHY47471.1 | RradSPS_1830 | RradSPS_2188 | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00062:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.562 |
AHY47422.1 | AHY47471.1 | RradSPS_2139 | RradSPS_2188 | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.577 |
AHY47470.1 | AHY47471.1 | RradSPS_2187 | RradSPS_2188 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.516 |
AHY47470.1 | pgk | RradSPS_2187 | RradSPS_1782 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.529 |
AHY47471.1 | AHY45548.1 | RradSPS_2188 | RradSPS_0265 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | T6PP: trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.587 |
AHY47471.1 | AHY46012.1 | RradSPS_2188 | RradSPS_0729 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | metH: methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.539 |
AHY47471.1 | AHY46013.1 | RradSPS_2188 | RradSPS_0730 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase. | 0.598 |
AHY47471.1 | AHY47113.1 | RradSPS_2188 | RradSPS_1830 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00062:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.562 |
AHY47471.1 | AHY47422.1 | RradSPS_2188 | RradSPS_2139 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.577 |
AHY47471.1 | AHY47470.1 | RradSPS_2188 | RradSPS_2187 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.516 |
AHY47471.1 | AHY47819.1 | RradSPS_2188 | RradSPS_2536 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00062:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.566 |
AHY47471.1 | AHY47857.1 | RradSPS_2188 | RradSPS_2574 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | 0.565 |
AHY47471.1 | pgk | RradSPS_2188 | RradSPS_1782 | COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. | COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.490 |