STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47471.1COG:COG0656: Aldo/keto reductases related to diketogulonate reductase [General function prediction only]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00798:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain. (257 aa)    
Predicted Functional Partners:
AHY46013.1
Homocysteine S-methyltransferase; COG:COG0646: Methionine synthase I (cobalamin-dependent) methyltransferase domain [Amino acid transport and metabolism]; Pfam:PF02574:Homocysteine S-methyltransferase; ProSiteProfiles:PS50970:Homocysteine S-methyltransferase; SUPERFAMILY:SSF82282:Homocysteine S-methyltransferase.
   
 0.598
AHY45548.1
T6PP: trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
  
 0.587
AHY47422.1
COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain.
 
 
0.577
AHY47819.1
COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00062:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain.
 
 
0.566
AHY47857.1
COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain.
 
 
0.565
AHY47113.1
COG:COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Pfam:PF00248:NADP-dependent oxidoreductase domain; Pfam:PF00248:NADP-dependent oxidoreductase domain; PRINTS:PR00069:Aldo/keto reductase subgroup; ProSitePatterns:PS00062:Aldo/keto reductase, conserved site; SUPERFAMILY:SSF51430:NADP-dependent oxidoreductase domain.
 
 
0.562
AHY46012.1
metH: methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.539
AHY47470.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.516
pgk
COG:COG0126: 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF00162:Phosphoglycerate kinase; Hamap:MF_00145:Phosphoglycerate kinase; Pfam:PF00162:Phosphoglycerate kinase; PIRSF:PIRSF000724:Phosphoglycerate kinase; PRINTS:PR00477:Phosphoglycerate kinase; ProSitePatterns:PS00111:Phosphoglycerate kinase, conserved site; SUPERFAMILY:SSF53748:Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.490
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.462
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]