STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47476.1TIGRFAM:TIGR00723:Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; COG:COG1838: Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain [Energy production and conversion]; Pfam:PF05683:Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; SUPERFAMILY:SSF117457:Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; ttdB_fumA_fumB. (194 aa)    
Predicted Functional Partners:
AHY47475.1
TIGRFAM:TIGR00722:Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; COG:COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain [Energy production and conversion]; Pfam:PF05681:Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; ttdA_fumA_fumB.
 
 0.999
AHY46383.1
COG:COG0281: Malic enzyme [Energy production and conversion]; Pfam:PF03949:Malic enzyme, NAD-binding; Pfam:PF03949:Malic enzyme, NAD-binding; PIRSF:PIRSF000106:Malic oxidoreductase; PRINTS:PR00072:Malic oxidoreductase; ProSitePatterns:PS00331:Malic enzyme, conserved site; SMART:SM00919:Malic enzyme, NAD-binding; SUPERFAMILY:SSF51735:No Description.
 
 
 0.979
AHY45296.1
COG:COG1053: Succinate dehydrogenase/fumarate reductase flavoprotein subunit [Energy production and conversion]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; SUPERFAMILY:SSF51905:No Description.
  
 
 0.959
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.959
AHY45297.1
TIGRFAM:TIGR00384:Succinate dehydrogenase/fumarate reductase iron-sulphur protein; COG:COG0479: Succinate dehydrogenase/fumarate reductase Fe-S protein subunit [Energy production and conversion]; Pfam:PF13085:Succinate dehydogenase/fumarate reductase N-terminal; ProSitePatterns:PS00197:2Fe-2S ferredoxin, iron-sulphur binding site; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF54292:2Fe-2S ferredoxin-type domain.
  
 
 0.954
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.934
AHY47138.1
TIGRFAM:TIGR01344:Malate synthase A; COG:COG2225: Malate synthase [Energy production and conversion]; Pfam:PF01274:Malate synthase; PIRSF:PIRSF001363:Malate synthase A; ProSitePatterns:PS00510:Malate synthase, conserved site; SUPERFAMILY:SSF51645:Malate synthase-like;KEGG: 00620; KEGG: 00630; UniPathway: UPA00703; malate_syn_A; Belongs to the malate synthase family.
     
 0.910
AHY46900.1
TIGRFAM:TIGR01798:Citrate synthase, type II; COG:COG0372: Citrate synthase [Energy production and conversion]; Pfam:PF00285:Citrate synthase-like; PIRSF:PIRSF001369:Citrate synthase, bacterial-type; PRINTS:PR00143:Citrate synthase-like; ProSitePatterns:PS00480:Citrate synthase active site; SUPERFAMILY:SSF48256:Citrate synthase-like, core;KEGG: 00020; KEGG: 00630; MetaCyc: PWY-5750; UniPathway: UPA00223; cit_synth_I; Belongs to the citrate synthase family.
  
 
 0.890
argH
TIGRFAM:TIGR00838:Argininosuccinate lyase; COG:COG0165: Argininosuccinate lyase [Amino acid transport and metabolism]; Pfam:PF00206:Fumarate lyase, N-terminal; Hamap:MF_00006:Argininosuccinate lyase; PRINTS:PR00145:Delta crystallin; ProSitePatterns:PS00163:Fumarate lyase, conserved site; SUPERFAMILY:SSF48557:L-Aspartase-like;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068.
    
 0.825
AHY45918.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase.
   
 
 0.807
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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