STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47510.1COG:COG1052: Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; ProSitePatterns:PS00670:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; SUPERFAMILY:SSF51735:No Description. (318 aa)    
Predicted Functional Partners:
AHY47547.1
COG:COG2379: Putative glycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF13660:Domain of unknown function DUF4147; Pfam:PF13660:Domain of unknown function DUF4147; SUPERFAMILY:SSF82544:No Description.
 
 0.957
AHY47545.1
COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF01565:FAD linked oxidase, N-terminal; Pfam:PF01565:FAD linked oxidase, N-terminal; ProSiteProfiles:PS51387:FAD-binding, type 2; SUPERFAMILY:SSF56176:FAD-binding, type 2.
   
 0.916
AHY47546.1
COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF02913:FAD-linked oxidase, C-terminal; Pfam:PF02913:FAD-linked oxidase, C-terminal; ProSiteProfiles:PS51387:FAD-binding, type 2; SUPERFAMILY:SSF56176:FAD-binding, type 2.
   
 0.916
AHY47873.1
TIGRFAM:TIGR00045:Glycerate kinase; COG:COG1929: Glycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF02595:Glycerate kinase; PIRSF:PIRSF006078:Glycerate kinase; SUPERFAMILY:SSF110738:Glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.916
AHY47138.1
TIGRFAM:TIGR01344:Malate synthase A; COG:COG2225: Malate synthase [Energy production and conversion]; Pfam:PF01274:Malate synthase; PIRSF:PIRSF001363:Malate synthase A; ProSitePatterns:PS00510:Malate synthase, conserved site; SUPERFAMILY:SSF51645:Malate synthase-like;KEGG: 00620; KEGG: 00630; UniPathway: UPA00703; malate_syn_A; Belongs to the malate synthase family.
  
 
 0.915
AHY47137.1
TIGRFAM:TIGR01346:Isocitrate lyase; COG:COG2224: Isocitrate lyase [Energy production and conversion]; Pfam:PF00463:Isocitrate lyase/phosphorylmutase; PIRSF:PIRSF001362:Isocitrate lyase; ProSitePatterns:PS00161:Isocitrate lyase/phosphorylmutase, conserved site; SUPERFAMILY:SSF51621:Pyruvate/Phosphoenolpyruvate kinase-like domain;KEGG: 00630; UniPathway: UPA00703; isocit_lyase.
     
 0.908
AHY46595.1
COG:COG3622: Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; PIRSF:PIRSF006241:Hydroxypyruvate isomerase-like; SUPERFAMILY:SSF51658:Xylose isomerase-like, TIM barrel domain; Belongs to the hyi family.
   
 
 0.907
AHY46596.1
TIGRFAM:TIGR01505:2-hydroxy-3-oxopropionate reductase; COG:COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Pfam:PF03446:6-phosphogluconate dehydrogenase, NADP-binding; PIRSF:PIRSF000103:Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type; ProSitePatterns:PS00895:3-hydroxyisobutyrate dehydrogenase-related, conserved site; SUPERFAMILY:SSF51735:No Description;KEGG: 00630; tartro_sem_red.
    
 0.904
AHY47544.1
COG:COG0247: Fe-S oxidoreductase [Energy production and conversion]; Pfam:PF02754:Cysteine-rich domain; Pfam:PF02754:Cysteine-rich domain; PIRSF:PIRSF000139:Glycolate oxidase, iron-sulphur subunit; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF54862:No Description.
    
 0.904
AHY46597.1
TIGRFAM:TIGR01504:Glyoxylate carboligase; COG:COG3960: Glyoxylate carboligase [General function prediction only]; Pfam:PF02776:Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; SUPERFAMILY:SSF52518:No Description;KEGG: 00630; UniPathway: UPA00864; glyox_carbo_lig; Belongs to the TPP enzyme family.
    
  0.901
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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