STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47526.1COG:COG0813: Purine-nucleoside phosphorylase [Nucleotide transport and metabolism]; Pfam:PF01048:Nucleoside phosphorylase domain; Pfam:PF01048:Nucleoside phosphorylase domain; ProSitePatterns:PS01232:Nucleoside phosphorylase, conserved site; SUPERFAMILY:SSF53167:No Description. (237 aa)    
Predicted Functional Partners:
AHY47525.1
TIGRFAM:TIGR02644:Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic; COG:COG0213: Thymidine phosphorylase [Nucleotide transport and metabolism]; Pfam:PF00591:Glycosyl transferase, family 3; PIRSF:PIRSF000478:Pyrimidine-nucleoside phosphorylase; ProSitePatterns:PS00647:Pyrimidine-nucleoside phosphorylase, conserved site; SMART:SM00941:Pyrimidine nucleoside phosphorylase, C-terminal; SUPERFAMILY:SSF52418:Glycosyl transferase, family 3;KEGG: 00240; KEGG: 00983; UniPathway: UPA00578; Y_phosphoryl.
 
 
 0.981
deoB
deoB: phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 0.962
AHY46797.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
 0.924
tdk
COG:COG1435: Thymidine kinase [Nucleotide transport and metabolism]; Pfam:PF00265:Thymidine kinase; Hamap:MF_00124:Thymidine kinase, subgroup; Pfam:PF00265:Thymidine kinase; PIRSF:PIRSF035805:Thymidine kinase; ProSitePatterns:PS00603:Thymidine kinase, conserved site; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.924
apt
Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.922
cobB-2
COG:COG0846: NAD-dependent protein deacetylases SIR2 family [Transcription]; Pfam:PF02146:Sirtuin family; Hamap:MF_01121:Sirtuin, classIII; Pfam:PF02146:Sirtuin family; ProSiteProfiles:PS50305:Sirtuin family, catalytic core domain; SUPERFAMILY:SSF52467:No Description; Belongs to the sirtuin family. Class III subfamily.
    
 0.919
AHY46527.1
COG:COG1488: Nicotinic acid phosphoribosyltransferase [Coenzyme metabolism]; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; PIRSF:PIRSF000484:Nicotinate phosphoribosyltransferase-related; SUPERFAMILY:SSF51690:Quinolinate phosphoribosyl transferase, C-terminal.
     
 0.911
AHY45408.1
HGPRTase: hypoxanthine phosphoribosyltransferase; TIGRFAM:TIGR01203:Hypoxanthine phosphoribosyl transferase; COG:COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Pfam:PF00156:Phosphoribosyltransferase domain; SUPERFAMILY:SSF53271:No Description;KEGG: 00230; KEGG: 00983; MetaCyc: PWY-6599; MetaCyc: PWY-6609; UniPathway: UPA00591; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.909
AHY46872.1
Upp: uracil phosphoribosyltransferase; TIGRFAM:TIGR01091:Uracil phosphoribosyl transferase; COG:COG0035: Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Pfam:PF00156:Phosphoribosyltransferase domain; SUPERFAMILY:SSF53271:No Description;KEGG: 00240; UniPathway: UPA00574; Belongs to the UPRTase family.
    
 0.909
AHY47257.1
HGPRTase: hypoxanthine phosphoribosyltransferase; TIGRFAM:TIGR01203:Hypoxanthine phosphoribosyl transferase; COG:COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Pfam:PF00156:Phosphoribosyltransferase domain; SUPERFAMILY:SSF53271:No Description;KEGG: 00230; KEGG: 00983; MetaCyc: PWY-6599; MetaCyc: PWY-6609; UniPathway: UPA00591; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.909
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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