STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argRArginine repressor; Regulates arginine biosynthesis genes. (162 aa)    
Predicted Functional Partners:
argJ
ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.995
argB
argB: acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.995
argC
argC: N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.979
argH
TIGRFAM:TIGR00838:Argininosuccinate lyase; COG:COG0165: Argininosuccinate lyase [Amino acid transport and metabolism]; Pfam:PF00206:Fumarate lyase, N-terminal; Hamap:MF_00006:Argininosuccinate lyase; PRINTS:PR00145:Delta crystallin; ProSitePatterns:PS00163:Fumarate lyase, conserved site; SUPERFAMILY:SSF48557:L-Aspartase-like;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068.
  
  
 0.968
argG
TIGRFAM:TIGR00032:Argininosuccinate synthase; COG:COG0137: Argininosuccinate synthase [Amino acid transport and metabolism]; Pfam:PF00764:Argininosuccinate synthase; Hamap:MF_00005:Argininosuccinate synthase, type 1 subfamily; ProSitePatterns:PS00565:Argininosuccinate synthase, conserved site; SUPERFAMILY:SSF69864:No Description;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.947
AHY47584.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
  
 0.939
argD
TIGRFAM:TIGR00707:Transaminase, Acetylornithine/Succinylornithine family; COG:COG4992: Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Hamap:MF_01107:Transaminase, Acetylornithine/Succinylornithine family; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.898
AHY47578.1
Hypothetical protein; COG:COG3603: Uncharacterized conserved protein [Function unknown]; Pfam:PF13840:Family description; Pfam:PF13840:Family description; PIRSF:PIRSF008459:Uncharacterised conserved protein UCP008459; SUPERFAMILY:SSF55021:No Description.
       0.745
AHY45753.1
TIGRFAM:TIGR00121:Biotin--acetyl-CoA-carboxylase ligase; COG:COG0340: Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;KEGG: 00780; birA_ligase.
 
   
 0.619
pheT
TIGRFAM:TIGR00472:Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial; COG:COG0072: Phenylalanyl-tRNA synthetase beta subunit [Translation ribosomal structure and biogenesis]; Pfam:PF03483:B3/B4 tRNA-binding domain; Hamap:MF_00283:Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial; ProSiteProfiles:PS51483:tRNA synthetase, B5-domain; SMART:SM00873:B3/B4 tRNA-binding domain; SUPERFAMILY:SSF56037:Phenylalanyl-tRNA synthetase, B3/B4;KEGG: 00970; pheT_bact.
  
  
 0.549
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (28%) [HD]
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