STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmNTIGR00048: 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (371 aa)    
Predicted Functional Partners:
AHY46716.1
TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family; TIGRFAM:TIGR00089:Methylthiotransferase; COG:COG0621: 2-methylthioadenine synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF04055:Radical SAM; ProSitePatterns:PS01278:Methylthiotransferase, conserved site; ProSiteProfiles:PS50926:TRAM domain; SMART:SM00729:Elongator protein 3/MiaB/NifB; SUPERFAMILY:SSF102114:No Description;KEGG: 00231; KEGG: 00540.
 
  
 0.829
AHY47640.1
COG:COG3428: Predicted membrane protein [Function unknown]; Pfam:PF03703:Bacterial PH domain; Pfam:PF03703:Bacterial PH domain; PIRSF:PIRSF026631:Uncharacterised conserved protein UCP026631.
  
    0.780
AHY47641.1
Hypothetical protein; COG:COG3402: Uncharacterized conserved protein [Function unknown]; Pfam:PF03703:Bacterial PH domain; Pfam:PF03703:Bacterial PH domain.
       0.773
AHY47643.1
Trypsin-like peptidase domain; COG:COG0265: Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain [Posttranslational modification protein turnover chaperones]; Pfam:PF13365:Trypsin-like peptidase domain; PRINTS:PR00834:Peptidase S1C; SUPERFAMILY:SSF50494:Trypsin-like cysteine/serine peptidase domain.
     
 0.713
AHY46777.1
TIGR00044: pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
     0.688
AHY46653.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.576
fmt
Fmt: methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    0.562
nusB
nusB: transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.543
rsmH
TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
 
 
 0.496
metG
metG: methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.465
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.