STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47662.1COG:COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Pfam:PF03446:6-phosphogluconate dehydrogenase, NADP-binding; Pfam:PF03446:6-phosphogluconate dehydrogenase, NADP-binding; PIRSF:PIRSF000103:Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type; SUPERFAMILY:SSF51735:No Description. (290 aa)    
Predicted Functional Partners:
AHY45633.1
GABAtrnsam: 4-aminobutyrate transaminase; TIGRFAM:TIGR00700:4-aminobutyrate aminotransferase, bacterial; COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase;KEGG: 00250; KEGG: 00280; KEGG: 00410; KEGG: 00640; KEGG: 00650; MetaCyc: PWY-4321; UniPathway: UPA00733; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
AHY45737.1
COG:COG4770: Acetyl/propionyl-CoA carboxylase alpha subunit [Lipid metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SMART:SM00878:Biotin carboxylase, C-terminal; SUPERFAMILY:SSF56059:No Description.
  
 
  0.815
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.806
AHY46907.1
TIGRFAM:TIGR02316:Propionate--CoA ligase; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00455:AMP-binding, conserved site; SUPERFAMILY:SSF56801:No Description;KEGG: 00640; MetaCyc: PWY-3941; UniPathway: UPA00946; propion_prpE.
  
 
  0.806
AHY45731.1
COG:COG4799: Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Pfam:PF01039:Carboxyl transferase; Pfam:PF01039:Carboxyl transferase; PRINTS:PR01070:Acetyl-CoA carboxylase carboxyl transferase, beta subunit; ProSiteProfiles:PS50980:Acetyl-coenzyme A carboxyltransferase, N-terminal; SUPERFAMILY:SSF52096:No Description.
  
 
  0.804
AHY45714.1
COG:COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes [Energy production and conversion]; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SUPERFAMILY:SSF52777:No Description.
     
  0.800
AHY46347.1
TIGRFAM:TIGR02425:4-carboxymuconolactone decarboxylase; COG:COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Pfam:PF02627:Carboxymuconolactone decarboxylase; SUPERFAMILY:SSF69118:No Description;KEGG: 00362; UniPathway: UPA00157; decarb_PcaC.
  
  
 0.521
AHY47661.1
COG:COG3146: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF04339:Protein of unknown function DUF482; Pfam:PF04339:Protein of unknown function DUF482; SUPERFAMILY:SSF55729:Acyl-CoA N-acyltransferase.
       0.470
AHY47663.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
       0.405
AHY47664.1
ABC-2 type transporter; COG:COG0842: ABC-type multidrug transport system permease component [Defense mechanisms]; Pfam:PF01061:ABC-2 type transporter.
       0.405
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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