STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47696.1COG:COG1132: ABC-type multidrug transport system ATPase and permease components [Defense mechanisms]; Pfam:PF00664:ABC transporter, transmembrane domain; Pfam:PF00664:ABC transporter, transmembrane domain; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase. (632 aa)    
Predicted Functional Partners:
AHY47975.1
ATPase family associated with various cellular activities (AAA); COG:COG1222: ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification protein turnover chaperones]; Pfam:PF00004:ATPase, AAA-type, core; ProSitePatterns:PS00674:ATPase, AAA-type, conserved site; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
 
 0.642
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.621
AHY47698.1
NUDIX domain; COG:COG1051: ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
  
 
 0.564
adk-2
Adk: adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
   0.527
AHY47697.1
COG:COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily;Reactome: REACT_14797.
       0.509
thrS
thrS: threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
   0.501
AHY47492.1
COG:COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification protein turnover chaperones]; Pfam:PF00226:DnaJ domain; PRINTS:PR00625:DnaJ domain; ProSiteProfiles:PS50076:DnaJ domain; SMART:SM00271:DnaJ domain; SUPERFAMILY:SSF46565:DnaJ domain.
  
 0.479
AHY47663.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 0.468
AHY46622.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.454
AHY47053.1
COG:COG3839: ABC-type sugar transport systems ATPase components [Carbohydrate transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; Belongs to the ABC transporter superfamily.
 
 
   
0.452
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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