STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47699.1COG:COG0346: Lactoylglutathione lyase and related lyases [Amino acid transport and metabolism]; Pfam:PF12681:Glyoxalase-like domain; Pfam:PF12681:Glyoxalase-like domain; ProSitePatterns:PS00934:Glyoxalase I, conserved site; SUPERFAMILY:SSF54593:No Description. (130 aa)    
Predicted Functional Partners:
AHY46853.1
COG:COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Pfam:PF12838:4Fe-4S binding domain; Pfam:PF12838:4Fe-4S binding domain; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF54862:No Description.
  
  
 0.496
AHY47700.1
TIGRFAM:TIGR00049:FeS cluster insertion protein; COG:COG0316: Uncharacterized conserved protein [Function unknown]; Pfam:PF01521:FeS cluster biogenesis; ProSitePatterns:PS01152:FeS cluster insertion, C-terminal, conserved site; SUPERFAMILY:SSF89360:FeS cluster biogenesis; Belongs to the HesB/IscA family.
  
    0.458
nuoD
NADH:ubiquinone oxidoreductase 49 kD subunit 7; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.430
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.