STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47706.1Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50109:Signal transduction histidine kinase, core; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain. (163 aa)    
Predicted Functional Partners:
AHY47705.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
   0.925
AHY45939.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.906
AHY45538.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.890
AHY45594.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.882
AHY47980.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.866
AHY46634.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.851
AHY45533.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00486:Signal transduction response regulator, C-terminal; Pfam:PF00486:Signal transduction response regulator, C-terminal; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00862:Signal transduction response regulator, C-terminal; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 0.848
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 0.846
AHY47708.1
GGDEF: diguanylate cyclase (GGDEF) domain; TIGRFAM:TIGR00254:GGDEF domain; COG:COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]; Pfam:PF00990:GGDEF domain; ProSiteProfiles:PS50887:GGDEF domain; SMART:SM00267:GGDEF domain; SUPERFAMILY:SSF55073:Adenylyl cyclase class-3/4/guanylyl cyclase.
   
 0.836
AHY47734.1
COG:COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00486:Signal transduction response regulator, C-terminal; Pfam:PF00486:Signal transduction response regulator, C-terminal; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00862:Signal transduction response regulator, C-terminal; SUPERFAMILY:SSF46894:Signal transduction response regulator, C-terminal effector.
 
 0.831
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.