STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47718.1COG:COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system permease component [Inorganic ion transport and metabolism]; Pfam:PF00528:Binding-protein-dependent transport systems inner membrane component; Pfam:PF00528:Binding-protein-dependent transport systems inner membrane component; ProSiteProfiles:PS50928:Binding-protein-dependent transport systems inner membrane component; SUPERFAMILY:SSF161098:No Description. (274 aa)    
Predicted Functional Partners:
AHY47717.1
COG:COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components [Inorganic ion transport and metabolism]; Pfam:PF09084:NMT1/THI5-like; Pfam:PF09084:NMT1/THI5-like; ProSiteProfiles:PS51318:Twin-arginine translocation pathway, signal sequence; SUPERFAMILY:SSF53850:No Description.
  
 0.996
AHY47719.1
COG:COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component [Inorganic ion transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 0.995
AHY47720.1
TIGRFAM:TIGR02357:Thiamine transporter ThiT/YuaJ; COG:COG3859: Predicted membrane protein [Function unknown]; Pfam:PF09515:Thiamine transporter ThiT/YuaJ; thia_yuaJ.
       0.773
thiM
thiM: hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
     
 0.555
AHY47711.1
NUDIX domain; COG:COG1051: ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Pfam:PF00293:NUDIX hydrolase domain; PRINTS:PR00502:NUDIX hydrolase; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like; Belongs to the Nudix hydrolase family.
 
     0.554
AHY47714.1
thiW: thiW protein; TIGRFAM:TIGR02359:ThiW; COG:COG4732: Predicted membrane protein [Function unknown]; Pfam:PF09512:ThiW; PIRSF:PIRSF024534:ThiW.
       0.514
AHY47716.1
TIGRFAM:TIGR00097:Phosphomethylpyrimidine kinase type-2; COG:COG0351: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme metabolism]; Pfam:PF08543:Phosphomethylpyrimidine kinase type-1; SUPERFAMILY:SSF53613:No Description;KEGG: 00730; UniPathway: UPA00060; HMP-P_kinase.
       0.514
thiE-2
thiE: thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.508
thiL
thiL: thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.503
AHY47713.1
Hypothetical protein; COG:COG3361: Uncharacterized conserved protein [Function unknown]; Pfam:PF09844:Protein of unknown function DUF2071; Pfam:PF09844:Protein of unknown function DUF2071; SUPERFAMILY:SSF160104:No Description.
       0.490
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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