STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47725.1COG:COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis transport and catabolism / General function prediction only]; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; PRINTS:PR00081:Glucose/ribitol dehydrogenase; ProSitePatterns:PS00061:Short-chain dehydrogenase/reductase, conserved site; SUPERFAMILY:SSF51735:No Description; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa)    
Predicted Functional Partners:
AHY45894.1
TIGRFAM:TIGR01746:Thioester reductase domain; COG:COG3320: Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00012:Phosphopantetheine attachment site; ProSiteProfiles:PS50075:Acyl carrier protein-like; SMART:SM00823:Polyketide synthase, phosphopantetheine-binding domain; SUPERFAMILY:SSF56801:No Description.
 
 
 
 0.919
AHY47724.1
Drug resistance MFS transporter, drugH+ antiporter-2 (14 Spanner) (DHA2) family; TIGRFAM:TIGR00711:Drug resistance transporter EmrB/QacA subfamily; COG:COG2814: Arabinose efflux permease [Carbohydrate transport and metabolism]; Pfam:PF07690:Major facilitator superfamily; PRINTS:PR01036:Tetracycline resistance protein TetB/drug resistance transporter; ProSiteProfiles:PS50850:Major facilitator superfamily domain; SUPERFAMILY:SSF103473:Major facilitator superfamily domain, general substrate transporter; efflux_EmrB.
  
    0.539
AHY47723.1
CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF13545:Crp-like helix-turn-helix domain; Pfam:PF13545:Crp-like helix-turn-helix domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00100:Cyclic nucleotide-binding domain; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like.
  
  0.495
AHY45893.1
COG:COG4221: Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; PIRSF:PIRSF000126:Short-chain dehydrogenase/reductase SDR; PRINTS:PR00081:Glucose/ribitol dehydrogenase; ProSitePatterns:PS00061:Short-chain dehydrogenase/reductase, conserved site; SMART:SM00822:Polyketide synthase/Fatty acid synthase, KR; SUPERFAMILY:SSF51735:No Description; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    
0.436
AHY46924.1
COG:COG4578: Glucitol operon activator [Transcription]; Pfam:PF06923:Glucitol operon activator.
  
    0.426
AHY46925.1
EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component; TIGRFAM:TIGR00821:Phosphotransferase system, enzyme II sorbitol-specific factor; COG:COG3730: Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Pfam:PF03608:Phosphotransferase system, enzyme II sorbitol-specific factor; PIRSF:PIRSF038321:Phosphotransferase system, enzyme II sorbitol-specific factor; ProSiteProfiles:PS51107:Phosphotransferase system, enzyme II sorbitol-specific factor.
  
    0.423
AHY45525.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 
 
 0.403
AHY46668.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; PIRSF:PIRSF000446:Malonyl CoA-acyl carrier protein transacylase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 
 
 0.403
AHY45801.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00583:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
   
    0.402
AHY46938.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00584:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
   
    0.402
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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