STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47763.1CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF00027:Cyclic nucleotide-binding domain; Pfam:PF00027:Cyclic nucleotide-binding domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00419:Transcription regulator HTH, Crp; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like. (256 aa)    
Predicted Functional Partners:
AHY47723.1
CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF13545:Crp-like helix-turn-helix domain; Pfam:PF13545:Crp-like helix-turn-helix domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00100:Cyclic nucleotide-binding domain; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like.
  
  
 
0.929
AHY45472.1
Cyclic nucleotide-binding domain; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF00027:Cyclic nucleotide-binding domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00100:Cyclic nucleotide-binding domain; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like.
  
  
 0.914
AHY45473.1
Cyclic nucleotide-binding domain; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF00027:Cyclic nucleotide-binding domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00100:Cyclic nucleotide-binding domain; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like.
  
  
  0.912
AHY46476.1
CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; COG:COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pfam:PF00027:Cyclic nucleotide-binding domain; Pfam:PF00027:Cyclic nucleotide-binding domain; ProSiteProfiles:PS50042:Cyclic nucleotide-binding domain; SMART:SM00100:Cyclic nucleotide-binding domain; SUPERFAMILY:SSF51206:Cyclic nucleotide-binding-like.
  
  
 
0.904
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.574
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 
 0.538
AHY47762.1
COG:COG0071: Molecular chaperone (small heat shock protein) [Posttranslational modification protein turnover chaperones]; Pfam:PF00011:Alpha crystallin/Hsp20 domain; Pfam:PF00011:Alpha crystallin/Hsp20 domain; ProSiteProfiles:PS01031:Alpha crystallin/Hsp20 domain; SUPERFAMILY:SSF49764:HSP20-like chaperone; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.463
rpoB
rpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.462
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.449
AHY45611.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2208: Serine phosphatase RsbU regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Pfam:PF07228:Protein phosphatase 2C (PP2C)-like; ProSiteProfiles:PS50112:PAS domain; SMART:SM00331:Protein phosphatase 2C (PP2C)-like; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.448
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.