STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47773.1FAD binding domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF01565:FAD linked oxidase, N-terminal; ProSiteProfiles:PS51387:FAD-binding, type 2; SUPERFAMILY:SSF56176:FAD-binding, type 2;MetaCyc: PWY-6386; UniPathway: UPA00219. (357 aa)    
Predicted Functional Partners:
AHY47920.1
TIGRFAM:TIGR03966:Heme/flavin dehydrogenase, Rv0694; COG:COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Energy production and conversion]; Pfam:PF01070:FMN-dependent dehydrogenase; PIRSF:PIRSF000138:Alpha-hydroxy acid dehydrogenase, FMN-dependent; ProSiteProfiles:PS51349:Alpha-hydroxy acid dehydrogenase, FMN-dependent; SUPERFAMILY:SSF51395:No Description; actino_HemFlav.
  
 0.961
AHY46083.1
TIGRFAM:TIGR01064:Pyruvate kinase; COG:COG0469: Pyruvate kinase [Carbohydrate transport and metabolism]; Pfam:PF00224:Pyruvate kinase, barrel; PRINTS:PR01050:Pyruvate kinase; ProSitePatterns:PS00110:Pyruvate kinase, active site; SUPERFAMILY:SSF51621:Pyruvate/Phosphoenolpyruvate kinase-like domain;KEGG: 00010; KEGG: 00230; KEGG: 00620; KEGG: 00710; MetaCyc: PWY-2221; Reactome: REACT_474; UniPathway: UPA00109; pyruv_kin.
   
 0.944
AHY46383.1
COG:COG0281: Malic enzyme [Energy production and conversion]; Pfam:PF03949:Malic enzyme, NAD-binding; Pfam:PF03949:Malic enzyme, NAD-binding; PIRSF:PIRSF000106:Malic oxidoreductase; PRINTS:PR00072:Malic oxidoreductase; ProSitePatterns:PS00331:Malic enzyme, conserved site; SMART:SM00919:Malic enzyme, NAD-binding; SUPERFAMILY:SSF51735:No Description.
  
 
 0.934
AHY47772.1
COG:COG1052: Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; ProSitePatterns:PS00670:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; SUPERFAMILY:SSF51735:No Description.
   
 0.931
AHY47178.1
COG:COG3875: Uncharacterized conserved protein [Function unknown]; Pfam:PF09861:Domain of unknown function DUF2088.
    
 0.916
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.912
AHY45765.1
Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.905
AHY46402.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
    
 0.905
AHY46544.1
Metallo-beta-lactamase superfamily; COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
    
 0.905
AHY46617.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
    
 0.905
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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