STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AHY47804.1DapE-ArgE: peptidase, ArgE/DapE family; TIGRFAM:TIGR01910:Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; ProSitePatterns:PS00759:ArgE/DapE/ACY1/CPG2/YscS, conserved site; SUPERFAMILY:SSF53187:No Description. (425 aa)    
Predicted Functional Partners:
argG
TIGRFAM:TIGR00032:Argininosuccinate synthase; COG:COG0137: Argininosuccinate synthase [Amino acid transport and metabolism]; Pfam:PF00764:Argininosuccinate synthase; Hamap:MF_00005:Argininosuccinate synthase, type 1 subfamily; ProSitePatterns:PS00565:Argininosuccinate synthase, conserved site; SUPERFAMILY:SSF69864:No Description;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.928
AHY47584.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.910
argD
TIGRFAM:TIGR00707:Transaminase, Acetylornithine/Succinylornithine family; COG:COG4992: Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Hamap:MF_01107:Transaminase, Acetylornithine/Succinylornithine family; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.909
argJ
ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
   
 
 0.906
AHY46529.1
Arginase; TIGRFAM:TIGR01229:Arginase; COG:COG0010: Arginase/agmatinase/formimionoglutamate hydrolase arginase family [Amino acid transport and metabolism]; Pfam:PF00491:Ureohydrolase; PIRSF:PIRSF036979:Ureohydrolase; PRINTS:PR00116:Ureohydrolase; ProSitePatterns:PS01053:Ureohydrolase, manganese-binding site; ProSiteProfiles:PS51409:Ureohydrolase; SUPERFAMILY:SSF52768:No Description;KEGG: 00330; MetaCyc: PWY-31; MetaCyc: PWY-4984; Reactome: REACT_13; UniPathway: UPA00158; rocF_arginase; Belongs to the arginase family.
  
 
 0.904
AHY47959.1
TIGRFAM:TIGR01900:Succinyl-diaminopimelate desuccinylase, DapE; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; SUPERFAMILY:SSF53187:No Description;KEGG: 00300; UniPathway: UPA00034; dapE-gram_pos.
  
     0.661
AHY47805.1
COG:COG0834: ABC-type amino acid transport/signal transduction systems periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]; Pfam:PF00497:Extracellular solute-binding protein, family 3; Pfam:PF00497:Extracellular solute-binding protein, family 3; ProSitePatterns:PS01039:Extracellular solute-binding protein, family 3, conserved site; SMART:SM00062:Extracellular solute-binding protein, family 3; SUPERFAMILY:SSF53850:No Description; Belongs to the bacterial solute-binding protein 3 family.
  
  
 0.515
AHY47120.1
COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; Pfam:PF01546:Peptidase M20; PIRSF:PIRSF037238:Peptidase M20, glutamate carboxypeptidase; ProSitePatterns:PS00758:ArgE/DapE/ACY1/CPG2/YscS, conserved site; SUPERFAMILY:SSF53187:No Description.
  
     0.444
AHY47806.1
TIGRFAM:TIGR01726:Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; COG:COG0765: ABC-type amino acid transport system permease component [Amino acid transport and metabolism]; Pfam:PF00528:Binding-protein-dependent transport systems inner membrane component; ProSiteProfiles:PS50928:Binding-protein-dependent transport systems inner membrane component; SUPERFAMILY:SSF161098:No Description; HEQRo_perm_3TM.
  
    0.429
AHY47784.1
COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; Pfam:PF01546:Peptidase M20; PIRSF:PIRSF037238:Peptidase M20, glutamate carboxypeptidase; SUPERFAMILY:SSF53187:No Description.
  
     0.424
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (28%) [HD]
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