STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47837.1COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045. (1490 aa)    
Predicted Functional Partners:
AHY47838.1
TIGRFAM:TIGR01317:Glutamate synthase, NADH/NADPH, small subunit 1; COG:COG0493: NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF07992:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; PRINTS:PR00419:Adrenodoxin reductase family signature; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF51971:No Description;UniPathway: UPA00045.
 0.999
AHY45729.1
COG:COG0334: Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Pfam:PF00208:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Pfam:PF00208:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; PIRSF:PIRSF000188:Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal; PRINTS:PR00082:Glutamate/phenylalanine/leucine/valine dehydrogenase; ProSitePatterns:PS00074:Glutamate/phenylalanine/leucine/va line dehydrogenase; SMART:SM00839:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SUPERFAMILY:SSF5 [...]
  
 
 0.995
AHY46403.1
TIGRFAM:TIGR00653:Glutamine synthetase type I; COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; ProSitePatterns:PS00181:Glutamine synthetase, glycine-rich site; SUPERFAMILY:SSF55931:No Description;KEGG: 00250; KEGG: 00330; KEGG: 00910; MetaCyc: PWY-3282.
  
 
 0.980
AHY48034.1
COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; Pfam:PF00120:Glutamine synthetase, catalytic domain; SUPERFAMILY:SSF55931:No Description.
  
 
 0.980
AHY45979.1
TIGRFAM:TIGR01304:IMP dehydrogenase-related 2; COG:COG0516: IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]; Pfam:PF00478:IMP dehydrogenase/GMP reductase; SUPERFAMILY:SSF51412:No Description;KEGG: 00121; KEGG: 00231; KEGG: 00520; KEGG: 00592; KEGG: 00633; KEGG: 00860; KEGG: 00906; KEGG: 00950; KEGG: 00981; IMP_DH_rel_2.
  
 
 0.978
carB
TIGRFAM:TIGR01369:Carbamoyl-phosphate synthase, large subunit; COG:COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Hamap:MF_01210_B:Carbamoyl-phosphate synthase, large subunit; PRINTS:PR00098:Carbamoyl-phosphate synthase large subunit, CPSase domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50975:ATP-grasp fold; SMART:SM01096:Carbamoyl [...]
  
 
 0.974
glmS
glmS: glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.969
AHY46968.1
COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; Pfam:PF00155:Aminotransferase, class I/classII; ProSitePatterns:PS00105:Aminotransferases, class-I, pyridoxal-phosphate-binding site; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
  
 
 0.962
AHY45708.1
COG:COG2902: NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; PIRSF:PIRSF036761:Bacterial NAD-glutamate dehydrogenase; SUPERFAMILY:SSF51735:No Description.
     
 0.950
glsA
TIGRFAM:TIGR03814:Glutaminase; COG:COG2066: Glutaminase [Amino acid transport and metabolism]; Pfam:PF04960:Glutaminase; Hamap:MF_00313:Glutaminase; SUPERFAMILY:SSF56601:Beta-lactamase/transpeptidase- like;KEGG: 00250; KEGG: 00330; KEGG: 00471; KEGG: 00910; Reactome: REACT_13; Reactome: REACT_13685; Gln_ase; Belongs to the glutaminase family.
     
 0.950
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.