STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47866.1Sss: transporter, solute:sodium symporter (SSS) family; TIGRFAM:TIGR00813:Sodium/solute symporter, subgroup; COG:COG4147: Predicted symporter [General function prediction only]; Pfam:PF00474:Sodium/solute symporter; ProSitePatterns:PS00457:Sodium/solute symporter, conserved site; ProSiteProfiles:PS50283:Sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (528 aa)    
Predicted Functional Partners:
AHY47865.1
COG:COG3162: Predicted membrane protein [Function unknown]; Pfam:PF04341:Protein of unknown function DUF485; Pfam:PF04341:Protein of unknown function DUF485.
 
  
 0.993
AHY47867.1
Acetyltransferase (GNAT) family; COG:COG1670: Acetyltransferases including N-acetylases of ribosomal proteins [Translation ribosomal structure and biogenesis]; Pfam:PF00583:GNAT domain; ProSiteProfiles:PS51186:GNAT domain; SUPERFAMILY:SSF55729:Acyl-CoA N-acyltransferase.
       0.548
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.533
AHY45706.1
COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description.
  
  
 0.516
AHY46907.1
TIGRFAM:TIGR02316:Propionate--CoA ligase; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00455:AMP-binding, conserved site; SUPERFAMILY:SSF56801:No Description;KEGG: 00640; MetaCyc: PWY-3941; UniPathway: UPA00946; propion_prpE.
  
  
 0.500
AHY45901.1
acetoacetate-CoA ligase; TIGRFAM:TIGR01217:Acetoacetyl-CoA synthase; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00455:AMP-binding, conserved site; SUPERFAMILY:SSF56801:No Description;KEGG: 00650; ac_ac_CoA_syn.
  
  
 0.491
AHY46956.1
TIGRFAM:TIGR02262:Benzoate-CoA ligase family; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description; benz_CoA_lig.
  
  
 0.491
AHY47122.1
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COG:COG1250: 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Pfam:PF02737:3-hydroxyacyl-CoA dehydrogenase, NAD binding; SUPERFAMILY:SSF51735:No Description;MetaCyc: PWY-1361; MetaCyc: PWY-5109; MetaCyc: PWY-5136; MetaCyc: PWY-5138; MetaCyc: PWY-5789; MetaCyc: PWY-6435; MetaCyc: PWY-735; UniPathway: UPA00659.
  
  
 0.435
AHY47868.1
COG:COG3339: Uncharacterized conserved protein [Function unknown]; Pfam:PF06803:Protein of unknown function DUF1232.
       0.433
AHY46900.1
TIGRFAM:TIGR01798:Citrate synthase, type II; COG:COG0372: Citrate synthase [Energy production and conversion]; Pfam:PF00285:Citrate synthase-like; PIRSF:PIRSF001369:Citrate synthase, bacterial-type; PRINTS:PR00143:Citrate synthase-like; ProSitePatterns:PS00480:Citrate synthase active site; SUPERFAMILY:SSF48256:Citrate synthase-like, core;KEGG: 00020; KEGG: 00630; MetaCyc: PWY-5750; UniPathway: UPA00223; cit_synth_I; Belongs to the citrate synthase family.
  
  
 0.422
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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