STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47874.1COG:COG1335: Amidases related to nicotinamidase [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00857:Isochorismatase-like; Pfam:PF00857:Isochorismatase-like; SUPERFAMILY:SSF52499:Isochorismatase-like. (201 aa)    
Predicted Functional Partners:
AHY46527.1
COG:COG1488: Nicotinic acid phosphoribosyltransferase [Coenzyme metabolism]; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; PIRSF:PIRSF000484:Nicotinate phosphoribosyltransferase-related; SUPERFAMILY:SSF51690:Quinolinate phosphoribosyl transferase, C-terminal.
  
 0.865
AHY47875.1
Pfam:PF00520:Ion transport domain; SUPERFAMILY:SSF81324:No Description.
       0.532
nadE
nadE: NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.525
nnrE
YjeF family C-terminal domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
    0.470
AHY45753.1
TIGRFAM:TIGR00121:Biotin--acetyl-CoA-carboxylase ligase; COG:COG0340: Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;KEGG: 00780; birA_ligase.
     
 0.467
AHY47873.1
TIGRFAM:TIGR00045:Glycerate kinase; COG:COG1929: Glycerate kinase [Carbohydrate transport and metabolism]; Pfam:PF02595:Glycerate kinase; PIRSF:PIRSF006078:Glycerate kinase; SUPERFAMILY:SSF110738:Glycerate kinase; Belongs to the glycerate kinase type-1 family.
  
    0.465
AHY47871.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50885:HAMP linker domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain.
  
   0.459
AHY47872.1
COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; Pfam:PF00939:Sodium/sulphate symporter.
  
    0.442
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.