STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47896.1COG:COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00455:AMP-binding, conserved site; SUPERFAMILY:SSF56801:No Description. (546 aa)    
Predicted Functional Partners:
AHY45894.1
TIGRFAM:TIGR01746:Thioester reductase domain; COG:COG3320: Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00012:Phosphopantetheine attachment site; ProSiteProfiles:PS50075:Acyl carrier protein-like; SMART:SM00823:Polyketide synthase, phosphopantetheine-binding domain; SUPERFAMILY:SSF56801:No Description.
 
0.794
AHY47895.1
COG:COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Pfam:PF02776:Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Pfam:PF02776:Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; SUPERFAMILY:SSF52518:No Description.
 
  
 0.681
AHY46962.1
COG:COG1024: Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Pfam:PF00378:Crotonase superfamily; Pfam:PF00378:Crotonase superfamily; ProSitePatterns:PS00166:Enoyl-CoA hydratase/isomerase, conserved site; SUPERFAMILY:SSF52096:No Description.
 
 
 0.609
AHY47122.1
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COG:COG1250: 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Pfam:PF02737:3-hydroxyacyl-CoA dehydrogenase, NAD binding; SUPERFAMILY:SSF51735:No Description;MetaCyc: PWY-1361; MetaCyc: PWY-5109; MetaCyc: PWY-5136; MetaCyc: PWY-5138; MetaCyc: PWY-5789; MetaCyc: PWY-6435; MetaCyc: PWY-735; UniPathway: UPA00659.
  
 
 0.573
AHY47893.1
SnoaL-like domain; COG:COG3631: Ketosteroid isomerase-related protein [General function prediction only]; Pfam:PF12680:Polyketide cyclase SnoaL-like domain; SUPERFAMILY:SSF54427:No Description.
  
    0.566
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.538
AHY45706.1
COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description.
 
 
0.529
AHY46956.1
TIGRFAM:TIGR02262:Benzoate-CoA ligase family; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description; benz_CoA_lig.
 
 
0.526
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.524
AHY47897.1
COG:COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Pfam:PF12697:Alpha/beta hydrolase family; Pfam:PF12697:Alpha/beta hydrolase family; PRINTS:PR00412:Epoxide hydrolase-like; SUPERFAMILY:SSF53474:No Description.
   
   0.515
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.