STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47938.1TIGRFAM:TIGR00656:Aspartate kinase, monofunctional class; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; PIRSF:PIRSF000726:Aspartate kinase, monofunctional class; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kin_monofn; Belongs to the aspartokinase family. (422 aa)    
Predicted Functional Partners:
AHY46333.1
COG:COG0136: Aspartate-semialdehyde dehydrogenase [Amino acid transport and metabolism]; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; PIRSF:PIRSF000148:Aspartate-semialdehyde dehydrogenase; SMART:SM00859:Semialdehyde dehydrogenase, NAD-binding; SUPERFAMILY:SSF55347:No Description; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.986
lysA
lysA: diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
   
 0.968
AHY46332.1
COG:COG0460: Homoserine dehydrogenase [Amino acid transport and metabolism]; Pfam:PF00742:Homoserine dehydrogenase, catalytic; Pfam:PF00742:Homoserine dehydrogenase, catalytic; PIRSF:PIRSF036497:Homoserine dehydrogenase, short; SUPERFAMILY:SSF55347:No Description.
 
 
 0.960
dapA
dapA: dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.942
dapB
dapB: dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.941
AHY46331.1
TIGRFAM:TIGR00657:Aspartate kinase domain; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kinases; Belongs to the aspartokinase family.
  
  
 
0.924
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
    
 0.862
AHY47354.1
TIGRFAM:TIGR01536:Asparagine synthase, glutamine-hydrolyzing; COG:COG0367: Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Pfam:PF00733:Asparagine synthase; PIRSF:PIRSF001589:Asparagine synthase, glutamine-hydrolyzing; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF52402:No Description;KEGG: 00250; KEGG: 00910; UniPathway: UPA00134; asn_synth_AEB.
  
 
 0.849
AHY46968.1
COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; Pfam:PF00155:Aminotransferase, class I/classII; ProSitePatterns:PS00105:Aminotransferases, class-I, pyridoxal-phosphate-binding site; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
  
 0.845
argG
TIGRFAM:TIGR00032:Argininosuccinate synthase; COG:COG0137: Argininosuccinate synthase [Amino acid transport and metabolism]; Pfam:PF00764:Argininosuccinate synthase; Hamap:MF_00005:Argininosuccinate synthase, type 1 subfamily; ProSitePatterns:PS00565:Argininosuccinate synthase, conserved site; SUPERFAMILY:SSF69864:No Description;KEGG: 00250; KEGG: 00330; MetaCyc: PWY-4983; MetaCyc: PWY-5; UniPathway: UPA00068; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.839
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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