STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
dapBdapB: dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (257 aa)    
Predicted Functional Partners:
dapA
dapA: dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.998
AHY47957.1
TIGRFAM:TIGR03537:Succinyldiaminopimelate transaminase, DapC; COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
 
  
 0.961
AHY47958.1
COG:COG2171: Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Pfam:PF00132:Bacterial transferase hexapeptide repeat; Pfam:PF00132:Bacterial transferase hexapeptide repeat; ProSitePatterns:PS00101:Hexapeptide transferase, conserved site; SUPERFAMILY:SSF51161:Trimeric LpxA-like; Belongs to the transferase hexapeptide repeat family.
 
 
 0.961
AHY47938.1
TIGRFAM:TIGR00656:Aspartate kinase, monofunctional class; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; PIRSF:PIRSF000726:Aspartate kinase, monofunctional class; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kin_monofn; Belongs to the aspartokinase family.
 
  
 0.941
lysA
lysA: diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.899
AHY46333.1
COG:COG0136: Aspartate-semialdehyde dehydrogenase [Amino acid transport and metabolism]; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; PIRSF:PIRSF000148:Aspartate-semialdehyde dehydrogenase; SMART:SM00859:Semialdehyde dehydrogenase, NAD-binding; SUPERFAMILY:SSF55347:No Description; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.854
dapF
DapF: diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
   
 0.802
carA
TIGRFAM:TIGR01368:Carbamoyl-phosphate synthase, small subunit; COG:COG0505: Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF00988:Carbamoyl-phosphate synthase, small subunit N-terminal domain; Hamap:MF_01209:Carbamoyl-phosphate synthase, small subunit; PRINTS:PR00099:Carbamoyl-phosphate synthase protein GATase domain signature; ProSiteProfiles:PS51273:Glutamine amidotransferase; SMART:SM01097:Carbamoyl-phosphate synthase, small subunit N-terminal domain; SUPERFAMILY:SSF52317:No Description;KEGG: 00240; KEGG: [...]
 
  
 0.773
AHY45753.1
TIGRFAM:TIGR00121:Biotin--acetyl-CoA-carboxylase ligase; COG:COG0340: Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;KEGG: 00780; birA_ligase.
  
  
 0.720
AHY46331.1
TIGRFAM:TIGR00657:Aspartate kinase domain; COG:COG0527: Aspartokinases [Amino acid transport and metabolism]; Pfam:PF00696:Aspartate/glutamate/uridylate kinase; ProSitePatterns:PS00324:Aspartate kinase, conserved site; SUPERFAMILY:SSF53633:Aspartate/glutamate/uridylate kinase;KEGG: 00260; KEGG: 00270; KEGG: 00300; MetaCyc: PWY-2941; UniPathway: UPA00034; UniPathway: UPA00050; UniPathway: UPA00051; asp_kinases; Belongs to the aspartokinase family.
 
  
 0.680
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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