STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dapFDapF: diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (264 aa)    
Predicted Functional Partners:
lysA
lysA: diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.973
AHY47957.1
TIGRFAM:TIGR03537:Succinyldiaminopimelate transaminase, DapC; COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
 
 0.969
murE
murE: UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
    
 0.949
AHY47959.1
TIGRFAM:TIGR01900:Succinyl-diaminopimelate desuccinylase, DapE; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; SUPERFAMILY:SSF53187:No Description;KEGG: 00300; UniPathway: UPA00034; dapE-gram_pos.
 
  
 0.943
AHY46859.1
COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; Pfam:PF01546:Peptidase M20; ProSitePatterns:PS00758:ArgE/DapE/ACY1/CPG2/YscS, conserved site; SUPERFAMILY:SSF53187:No Description.
    
 0.933
carB
TIGRFAM:TIGR01369:Carbamoyl-phosphate synthase, large subunit; COG:COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Hamap:MF_01210_B:Carbamoyl-phosphate synthase, large subunit; PRINTS:PR00098:Carbamoyl-phosphate synthase large subunit, CPSase domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50975:ATP-grasp fold; SMART:SM01096:Carbamoyl [...]
    
 0.908
AHY46333.1
COG:COG0136: Aspartate-semialdehyde dehydrogenase [Amino acid transport and metabolism]; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; Pfam:PF02774:Semialdehyde dehydrogenase, dimerisation domain; PIRSF:PIRSF000148:Aspartate-semialdehyde dehydrogenase; SMART:SM00859:Semialdehyde dehydrogenase, NAD-binding; SUPERFAMILY:SSF55347:No Description; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.837
dapB
dapB: dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.802
dapA
dapA: dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.790
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
  
  
 0.695
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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