STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47946.1TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF00072:Signal transduction response regulator, receiver domain; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily; sensory_box. (759 aa)    
Predicted Functional Partners:
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
0.996
AHY45891.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50112:PAS domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
 
 0.996
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 
0.996
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 
0.995
AHY47707.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50885:HAMP linker domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
 
 
0.994
AHY45611.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2208: Serine phosphatase RsbU regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Pfam:PF07228:Protein phosphatase 2C (PP2C)-like; ProSiteProfiles:PS50112:PAS domain; SMART:SM00331:Protein phosphatase 2C (PP2C)-like; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
 
 
 0.960
AHY47183.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COG:COG4251: Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50109:Signal transduction histidine kinase, core; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain.
 
 
 
 0.916
AHY47945.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 
 0.898
AHY47824.1
GGDEF: diguanylate cyclase (GGDEF) domain; TIGRFAM:TIGR00254:GGDEF domain; COG:COG5001: Predicted signal transduction protein containing a membrane domain an EAL and a GGDEF domain [Signal transduction mechanisms]; Pfam:PF00563:Diguanylate phosphodiesterase, EAL domain; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00052:Diguanylate phosphodiesterase, EAL domain; SUPERFAMILY:SSF141868:Diguanylate phosphodiesterase, EAL domain.
  
 
 0.876
AHY46004.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2200: FOG: EAL domain [Signal transduction mechanisms]; Pfam:PF00563:Diguanylate phosphodiesterase, EAL domain; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00052:Diguanylate phosphodiesterase, EAL domain; SUPERFAMILY:SSF141868:Diguanylate phosphodiesterase, EAL domain; sensory_box.
 
 
0.864
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (18%) [HD]
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