STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47959.1TIGRFAM:TIGR01900:Succinyl-diaminopimelate desuccinylase, DapE; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; SUPERFAMILY:SSF53187:No Description;KEGG: 00300; UniPathway: UPA00034; dapE-gram_pos. (364 aa)    
Predicted Functional Partners:
AHY47957.1
TIGRFAM:TIGR03537:Succinyldiaminopimelate transaminase, DapC; COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
    
 0.971
dapF
DapF: diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.943
AHY46859.1
COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; Pfam:PF01546:Peptidase M20; ProSitePatterns:PS00758:ArgE/DapE/ACY1/CPG2/YscS, conserved site; SUPERFAMILY:SSF53187:No Description.
  
  
 
0.928
argD
TIGRFAM:TIGR00707:Transaminase, Acetylornithine/Succinylornithine family; COG:COG4992: Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Hamap:MF_01107:Transaminase, Acetylornithine/Succinylornithine family; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.909
AHY47958.1
COG:COG2171: Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Pfam:PF00132:Bacterial transferase hexapeptide repeat; Pfam:PF00132:Bacterial transferase hexapeptide repeat; ProSitePatterns:PS00101:Hexapeptide transferase, conserved site; SUPERFAMILY:SSF51161:Trimeric LpxA-like; Belongs to the transferase hexapeptide repeat family.
 
  
 0.845
AHY47804.1
DapE-ArgE: peptidase, ArgE/DapE family; TIGRFAM:TIGR01910:Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; ProSitePatterns:PS00759:ArgE/DapE/ACY1/CPG2/YscS, conserved site; SUPERFAMILY:SSF53187:No Description.
  
     0.661
AHY47960.1
Bacterial extracellular solute-binding protein; COG:COG1653: ABC-type sugar transport system periplasmic component [Carbohydrate transport and metabolism]; Pfam:PF01547:Bacterial extracellular solute-binding, family 1; SUPERFAMILY:SSF53850:No Description.
       0.592
lysA
lysA: diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.584
argC
argC: N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
 
 0.477
AHY46739.1
COG:COG0463: Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis outer membrane]; Pfam:PF00535:Glycosyl transferase, family 2; SUPERFAMILY:SSF53448:No Description.
  
 
 0.420
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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