STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47969.1F420-dependent oxidoreductase, G6PDH family; TIGRFAM:TIGR03557:F420-dependent glucose-6-phosphate dehydrogenase-related; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain. (333 aa)    
Predicted Functional Partners:
AHY47394.1
TIGRFAM:TIGR00026:Deazaflavin-dependent nitroreductase; Pfam:PF04075:Deazaflavin-dependent nitroreductase;KEGG: 00121; KEGG: 00231; KEGG: 00520; KEGG: 00592; KEGG: 00633; KEGG: 00860; KEGG: 00906; KEGG: 00950; KEGG: 00981; hi_GC_TIGR00026.
  
   
 0.751
AHY45715.1
COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
  
     0.748
AHY46151.1
TIGRFAM:TIGR01819:LPPG:Fo 2-phospho-L-lactate transferase; COG:COG0391: Uncharacterized conserved protein [Function unknown]; Pfam:PF01933:LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052; Hamap:MF_01257:LPPG:Fo 2-phospho-L-lactate transferase; SUPERFAMILY:SSF142338:No Description;KEGG: 00440; KEGG: 00513; KEGG: 00564; KEGG: 00600; UniPathway: UPA00071.
 
   
 0.705
AHY46154.1
TIGRFAM:TIGR01916:Coenzyme F420:L-glutamate ligase, bacterial and archeal; COG:COG1478: Uncharacterized conserved protein [Function unknown]; Pfam:PF01996:Coenzyme F420:L-glutamate ligase-like domain; SUPERFAMILY:SSF144010:No Description;KEGG: 00380; UniPathway: UPA00071.
 
   
 0.705
fbiD
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.597
AHY47717.1
COG:COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components [Inorganic ion transport and metabolism]; Pfam:PF09084:NMT1/THI5-like; Pfam:PF09084:NMT1/THI5-like; ProSiteProfiles:PS51318:Twin-arginine translocation pathway, signal sequence; SUPERFAMILY:SSF53850:No Description.
  
  
 0.592
AHY46124.1
Putative F420-dependent oxidoreductase, MSMEG_2256 family; TIGRFAM:TIGR03617:Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
  
     0.562
AHY47970.1
COG:COG4552: Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Pfam:PF13530:Sterol carrier protein domain; Pfam:PF13530:Sterol carrier protein domain; ProSiteProfiles:PS51186:GNAT domain; SUPERFAMILY:SSF55729:Acyl-CoA N-acyltransferase.
       0.550
AHY47971.1
COG:COG1695: Predicted transcriptional regulators [Transcription]; Pfam:PF03551:Transcription regulator PadR N-terminal; SUPERFAMILY:SSF46785:No Description.
       0.550
AHY45894.1
TIGRFAM:TIGR01746:Thioester reductase domain; COG:COG3320: Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00012:Phosphopantetheine attachment site; ProSiteProfiles:PS50075:Acyl carrier protein-like; SMART:SM00823:Polyketide synthase, phosphopantetheine-binding domain; SUPERFAMILY:SSF56801:No Description.
   
 
 0.416
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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