STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY47975.1ATPase family associated with various cellular activities (AAA); COG:COG1222: ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification protein turnover chaperones]; Pfam:PF00004:ATPase, AAA-type, core; ProSitePatterns:PS00674:ATPase, AAA-type, conserved site; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase. (523 aa)    
Predicted Functional Partners:
AHY45285.1
Dnan: DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiat [...]
  
 
 0.807
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.746
AHY46018.1
COG:COG1136: ABC-type antimicrobial peptide transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
     0.729
AHY45565.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.724
AHY47195.1
COG:COG1122: ABC-type cobalt transport system ATPase component [Inorganic ion transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
     0.704
cysS
cysS: cysteine--tRNA ligase; TIGRFAM:TIGR00435:Cysteine-tRNA ligase; COG:COG0215: Cysteinyl-tRNA synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF01406:Cysteinyl-tRNA synthetase/mycothiol ligase; Hamap:MF_00041:Cysteine-tRNA ligase; PRINTS:PR00983:Cysteinyl-tRNA synthetase/mycothiol ligase; SMART:SM00840:Cysteinyl-tRNA synthetase, class Ia, DALR; SUPERFAMILY:SSF52374:No Description;KEGG: 00970; Reactome: REACT_71; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.681
AHY47539.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.673
AHY46302.1
COG:COG3638: ABC-type phosphate/phosphonate transport system ATPase component [Inorganic ion transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
     0.668
AHY47663.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.667
AHY45763.1
TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; TIGRFAM:TIGR00042:Ham1-like protein; COG:COG0127: Xanthosine triphosphate pyrophosphatase [Nucleotide transport and metabolism]; Pfam:PF01725:Ham1-like protein; SUPERFAMILY:SSF52972:No Description;KEGG: 00230; KEGG: 00730; Belongs to the HAM1 NTPase family.
  
  
 0.653
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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