STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY48015.1COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase. (459 aa)    
Predicted Functional Partners:
AHY45296.1
COG:COG1053: Succinate dehydrogenase/fumarate reductase flavoprotein subunit [Energy production and conversion]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; SUPERFAMILY:SSF51905:No Description.
   
 0.927
AHY45351.1
COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.926
AHY45633.1
GABAtrnsam: 4-aminobutyrate transaminase; TIGRFAM:TIGR00700:4-aminobutyrate aminotransferase, bacterial; COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase;KEGG: 00250; KEGG: 00280; KEGG: 00410; KEGG: 00640; KEGG: 00650; MetaCyc: PWY-4321; UniPathway: UPA00733; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.926
AHY45297.1
TIGRFAM:TIGR00384:Succinate dehydrogenase/fumarate reductase iron-sulphur protein; COG:COG0479: Succinate dehydrogenase/fumarate reductase Fe-S protein subunit [Energy production and conversion]; Pfam:PF13085:Succinate dehydogenase/fumarate reductase N-terminal; ProSitePatterns:PS00197:2Fe-2S ferredoxin, iron-sulphur binding site; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF54292:2Fe-2S ferredoxin-type domain.
   
 
 0.911
AHY46900.1
TIGRFAM:TIGR01798:Citrate synthase, type II; COG:COG0372: Citrate synthase [Energy production and conversion]; Pfam:PF00285:Citrate synthase-like; PIRSF:PIRSF001369:Citrate synthase, bacterial-type; PRINTS:PR00143:Citrate synthase-like; ProSitePatterns:PS00480:Citrate synthase active site; SUPERFAMILY:SSF48256:Citrate synthase-like, core;KEGG: 00020; KEGG: 00630; MetaCyc: PWY-5750; UniPathway: UPA00223; cit_synth_I; Belongs to the citrate synthase family.
  
 0.870
pckA
pckA: phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.867
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.829
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.823
AHY45700.1
TIGRFAM:TIGR00239:2-oxoglutarate dehydrogenase, E1 component; COG:COG0567: 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; PIRSF:PIRSF000157:2-oxoglutarate dehydrogenase, E1 component; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description;KEGG: 00020; KEGG: 00310; KEGG: 00380; MetaCyc: PWY-5084; 2oxo_dh_E1.
   
 
 0.822
AHY46554.1
COG:COG0473: Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Pfam:PF00180:Isopropylmalate dehydrogenase-like domain; Pfam:PF00180:Isopropylmalate dehydrogenase-like domain; ProSitePatterns:PS00470:Isocitrate/isopropylmalate dehydrogenase, conserved site; SUPERFAMILY:SSF53659:No Description.
  
 0.820
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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