STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AHY48027.1Bacterial regulatory protein, luxR family; COG:COG2771: DNA-binding HTH domain-containing proteins [Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF46894:Signal transduction response regulator, C-terminal effector. (369 aa)    
Predicted Functional Partners:
AHY47014.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF46894:Signal transduction response regulator, C-terminal effector.
 
 
 0.659
AHY46482.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 0.606
AHY46279.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 0.604
AHY47945.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 0.590
AHY46479.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50110:Signal transduction response regulator, receiver domain; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY- [...]
 
 
 0.587
AHY48028.1
Cupin domain; COG:COG1917: Uncharacterized conserved protein contains double-stranded beta-helix domain [Function unknown]; Pfam:PF07883:Cupin 2, conserved barrel; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
 
     0.586
AHY46480.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 0.562
AHY47386.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00072:Signal transduction response regulator, receiver domain; Pfam:PF00072:Signal transduction response regulator, receiver domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00448:Signal transduction response regulator, receiver domain; SUPERFAMILY:SSF52172:CheY-like superfamily.
 
 
 0.543
AHY47385.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50109:Signal transduction histidine kinase, core; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain.
  
     0.540
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.536
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.