STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY48042.1COG:COG0265: Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain [Posttranslational modification protein turnover chaperones]; Pfam:PF13365:Trypsin-like peptidase domain; Pfam:PF13365:Trypsin-like peptidase domain; PRINTS:PR00834:Peptidase S1C; ProSiteProfiles:PS50106:PDZ domain; SMART:SM00228:PDZ domain; SUPERFAMILY:SSF50494:Trypsin-like cysteine/serine peptidase domain. (317 aa)    
Predicted Functional Partners:
AHY48043.1
COG:COG0265: Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain [Posttranslational modification protein turnover chaperones]; Pfam:PF13180:PDZ domain; Pfam:PF13180:PDZ domain; PRINTS:PR00834:Peptidase S1C; ProSiteProfiles:PS50106:PDZ domain; SMART:SM00228:PDZ domain; SUPERFAMILY:SSF50494:Trypsin-like cysteine/serine peptidase domain.
 
    
0.837
AHY47687.1
Trypsin-like peptidase domain; COG:COG0265: Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain [Posttranslational modification protein turnover chaperones]; Pfam:PF13365:Trypsin-like peptidase domain; PRINTS:PR00834:Peptidase S1C; ProSiteProfiles:PS51257:Prokaryotic membrane lipoprotein lipid attachment site profile.; SUPERFAMILY:SSF50494:Trypsin-like cysteine/serine peptidase domain.
  
     0.774
AHY48041.1
COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF00196:Transcription regulator LuxR, C-terminal; Pfam:PF00196:Transcription regulator LuxR, C-terminal; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50043:Transcription regulator LuxR, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF46894:Signal transduction response regulator, C-terminal effector.
       0.773
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.568
AHY46470.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
  
    0.542
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.538
leuS
TIGRFAM:TIGR00396:Leucine-tRNA ligase, bacterial/mitochondrial; COG:COG0495: Leucyl-tRNA synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF13603:Leucyl-tRNA synthetase, editing domain; Hamap:MF_00049_B:Leucine-tRNA ligase, bacterial/mitochondrial; PRINTS:PR00985:Leucine-tRNA ligase, bacterial/mitochondrial; SUPERFAMILY:SSF52374:No Description;KEGG: 00290; KEGG: 00970; leuS_bact; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.509
AHY45490.1
TPR repeat; COG:COG3063: Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF13414:TPR repeat; ProSiteProfiles:PS50005:Tetratricopeptide repeat; SMART:SM00028:Tetratricopeptide repeat; SUPERFAMILY:SSF48452:No Description.
   
 0.459
rsfS
Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
   0.447
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.415
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (20%) [HD]
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