STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A251RM22Putative cyclin A2, chordate; Belongs to the cyclin family. (451 aa)    
Predicted Functional Partners:
WEE1
Putative WEE1-like kinase; Belongs to the protein kinase superfamily.
   
 0.919
A0A251TDW3
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.885
CKS1
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.885
CCH11
Putative cyclin-H1-1; Belongs to the cyclin family.
     
 0.841
A0A251RQ30
Putative transducin/WD40 repeat-like superfamily protein.
    
 0.822
CDC2D
Putative cell division control protein; Belongs to the protein kinase superfamily.
   
 0.802
A0A251UEB0
Putative serine/threonine-protein kinase, Ulk1/Ulk2; Belongs to the protein kinase superfamily.
   
 0.802
CDKB2:2
Putative cyclin-dependent kinase B2,2; Belongs to the protein kinase superfamily.
   
 0.802
ORC1B
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.801
CDC2A
Putative cell division control protein; Belongs to the protein kinase superfamily.
   
 0.796
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.