Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ATGRX4Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (158 aa)    
Predicted Functional Partners:
A0A251SAJ4
Putative bolA-like family protein; Belongs to the BolA/IbaG family.
  
 
 0.917
A0A251UNX0
Putative bolA-like family protein; Belongs to the BolA/IbaG family.
  
 
 0.902
A0A251V8B7
Putative bolA protein, Fe-S metabolism associated domain, SufE-like protein.
  
 
 0.863
DRE2
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
   
 
 0.840
DRE2-2
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
   
 
 0.840
A0A251T3H0
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family.
    
 
 0.834
A0A251UFP5
Putative bolA protein; Belongs to the BolA/IbaG family.
  
 
 0.829
A0A251T4B4
Putative feS cluster biogenesi, FeS cluster insertion protein.
  
 0.757
A0A251T4X1
Putative feS cluster biogenesi, FeS cluster insertion protein.
  
 0.757
A0A251U4V6
Putative iron-sulfur cluster biosynthesis family protein.
  
 0.757
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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